Major progress in studying the biology of schistosomes had been achieved since the late
1960s with the successful laboratory cultivation of the parasite's life cycle stages in the …

Schistosomiasis control is heavily reliant on the drug praziquantel (PZQ), which is used as
preventive chemotherapy as part of national helminth control strategies. Given the heavy …

Fibrosis is a potentially debilitating disease with high morbidity rates. It is estimated that half
of all deaths that occur in the USA are attributed to fibrotic disorders. Fibrotic disorders are …

Background Schistosomiasis is one of the most prevalent helminthic infections worldwide.
Praziquantel (PZQ) resistance poses a possible danger to the disease's ability to be …

Background Hepatic schistosomiasis is considered to be one of the most prevalent forms of
chronic liver disease in the world due to its complication of liver fibrosis. The demonstration …

Oogram methodology permitted a direct assessment of the fecundity of Schistosoma
mansoni and the passage of parasite eggs from mesenteric vessels into the intestinal lumen …

This study investigates the possible use of pentoxifylline (PTX), with antifibrotic and anti-
inflammatory properties, as adjuvant in treatment of schistosomal liver fibrosis through …

Cratylia mollis is a natural forage plant from the Northeast of Brazil. C. mollis seed lectin
(Cramoll) containing molecular forms 1 and 4 (Cramoll 1, 4) has shown anti-inflammatory …

The purpose of this study was to determine cytokine patterns in experimental
schistosomiasis mansoni infected mice treated with silymarin. The study was conducted …

A method for the combinative oxidative homo dimerization and cyanation of free indole
derivatives catalysed by TEMPO along with silver carbonate was demonstrated for the first …