Signaling pathways in inflammation and anti-inflammatory therapies

YT Yeung, F Aziz, A Guerrero-Castilla… - Current …, 2018 - ingentaconnect.com
During the past decade, an abundance of new evidence highlighted the importance of
inflammation in the development of chronic pathologies such as neurodegeneration, cancer …

Antibodies targeting the transferrin receptor 1 (TfR1) as direct anti-cancer agents

PV Candelaria, LS Leoh, ML Penichet… - Frontiers in …, 2021 - frontiersin.org
The transferrin receptor 1 (TfR1), also known as cluster of differentiation 71 (CD71), is a type
II transmembrane glycoprotein that binds transferrin (Tf) and performs a critical role in …

Interplay between inflammation and cancer

R Khandia, A Munjal - Advances in protein chemistry and structural biology, 2020 - Elsevier
During the 19th century, for the first time, the linkage between inflammation and cancer was
established. Inflammatory microenvironment is an essential component of the tumor …

Mechanobiology of macrophages: how physical factors coregulate macrophage plasticity and phagocytosis

N Jain, J Moeller, V Vogel - Annual review of biomedical …, 2019 - annualreviews.org
In addition to their early-recognized functions in host defense and the clearance of apoptotic
cell debris, macrophages play vital roles in tissue development, homeostasis, and repair. If …

Central role of oxidative stress in age‐related macular degeneration: evidence from a review of the molecular mechanisms and animal models

S Abokyi, CH To, TT Lam, DY Tse - Oxidative medicine and …, 2020 - Wiley Online Library
Age‐related macular degeneration (AMD) is a common cause of visual impairment in the
elderly. There are very limited therapeutic options for AMD with the predominant therapies …

The effects of hyperbaric oxygenation on oxidative stress, inflammation and angiogenesis

SD De Wolde, RH Hulskes, RP Weenink… - Biomolecules, 2021 - mdpi.com
Hyperbaric oxygen therapy (HBOT) is commonly used as treatment in several diseases,
such as non-healing chronic wounds, late radiation injuries and carbon monoxide …

Hyperbaric oxygen therapy reduces oxidative stress and inflammation, and increases growth factors favouring the healing process of diabetic wounds

X Capó, M Monserrat-Mesquida… - International journal of …, 2023 - mdpi.com
Hyperbaric oxygen therapy (HBOT) is the clinical application of oxygen at pressures higher
than atmospheric pressure. HBOT has been effectively used to manage diverse clinical …

Syndecans in inflammation at a glance

S Gopal - Frontiers in immunology, 2020 - frontiersin.org
Syndecans are transmembrane proteoglycans with heparan and chondroitin sulfate chains
attached to their extracellular domain. Like many proteoglycans, they interact with a large …

Retinopathy of prematurity: inflammation, choroidal degeneration, and novel promising therapeutic strategies

JC Rivera, M Holm, D Austeng, TS Morken… - Journal of …, 2017 - Springer
Retinopathy of prematurity (ROP) is an important cause of childhood blindness globally, and
the incidence is rising. The disease is characterized by initial arrested retinal vascularization …

The molecular adaptive responses of skeletal muscle to high-intensity exercise/training and hypoxia

J Li, Y Li, MM Atakan, J Kuang, Y Hu, DJ Bishop, X Yan - Antioxidants, 2020 - mdpi.com
High-intensity exercise/training, especially interval exercise/training, has gained popularity
in recent years. Hypoxic training was introduced to elite athletes half a century ago and has …