The cell biology of fertilization: Gamete attachment and fusion

KK Siu, VHB Serrão, A Ziyyat, JE Lee - Journal of Cell Biology, 2021 - rupress.org
Fertilization is defined as the union of two gametes. During fertilization, sperm and egg fuse
to form a diploid zygote to initiate prenatal development. In mammals, fertilization involves …

SPINKs in tumors: potential therapeutic targets

C Liao, Q Wang, J An, M Zhang, J Chen, X Li… - Frontiers in …, 2022 - frontiersin.org
The serine protease inhibitor Kazal type (SPINK) family includes SPINK1-14 and is the
largest branch in the serine protease inhibitor family. SPINKs play an important role in …

[HTML][HTML] Transcriptome analysis of the testes of male chickens with high and low sperm motility

Z Du, WT Li, C Liu, CX Wang, DX Wang, SP Zhu… - Poultry Science, 2022 - Elsevier
The reproductive performance of chicken breeders has significant economic importance in
the poultry industry, and sperm motility is an indicator of reproductive performance. This …

Extracellular vesicle-encapsulated miR-21-5p in seminal plasma prevents sperm capacitation via Vinculin inhibition

Y Xie, Z Xu, C Wu, C Zhou, X Zhang, T Gu, J Yang… - Theriogenology, 2022 - Elsevier
To penetrate the zona pellucida before sperm-egg binding, sperm must undergo highly time-
controlled capacitation and acrosome reaction in the female reproductive tract. Our previous …

The other side of capacitation: role of mouse male molecules in the regulation of time and place of capacitation

AR Nicolli, A Cesari - Reproduction, 2023 - rep.bioscientifica.com
In brief Capacitation is regulated by decapacitation factors secreted by male ducts and
accessory sex glands. This revision is focused on targets and events regulated by …

Supplementation of Schisandrin B in Semen Extender Improves Quality and Oxidation Resistance of Boar Spermatozoa Stored at 4° C

Y Xie, Z Chen, Y Wang, X Peng, N Feng, X Wang… - Animals, 2023 - mdpi.com
Simple Summary Sch B is the active component extracted from Sch B Fructus. It shows
reproductive protection and spermatogenesis effects in animals. As far as we know, no …

A mouse testis serine protease, TESP1, as the potential SPINK3 receptor protein on mouse sperm acrosome

SS Ramachandran, R Balu… - Molecular Human …, 2021 - academic.oup.com
Serine protease inhibitor Kazal type 3 (SPINK3) from mouse seminal vesicles is a Kazal-
type trypsin inhibitor. It has been shown to bind to the sperm acrosome and modify sperm …

A New Gene SCY3 Homologous to Scygonadin Showing Antibacterial Activity and a Potential Role in the Sperm Acrosome Reaction of Scylla paramamosain

S Long, F Chen, J Li, Y Yang, KJ Wang - International Journal of …, 2023 - mdpi.com
In the study, a new gene homologous to the known antimicrobial peptide Scygonadin was
identified in mud crab Scylla paramamosain and named SCY3. The full-length sequences of …

How, where and when is SPINK3 bound and removed from mouse sperm?

AR Nicolli, CAI Alonso, C Otamendi, M Cerletti… - …, 2022 - rep.bioscientifica.com
Sperm capacitation in mammals is a fundamental requirement to acquire their fertilizing
capacity. Little is known about the action mechanism of the molecules that prevent …

PROTEIN FACTORS OF CAPACITATION AND DECAPACITATION IN CANINE SEMINAL PLASMA.

TSS TSVETKOV… - Bulgarian Journal of …, 2024 - search.ebscohost.com
The aim of the present study was to determine the proteins in canine seminal plasma with
direct effect on specific sperm parameters during fertilisation. The influence of seminal …