Novel therapeutic approaches for Alzheimer's disease: an updated review
Alzheimer's disease (AD) is a progressive neurodegenerative disease and accounts for
most cases of dementia. The prevalence of AD has increased in the current rapidly aging …
most cases of dementia. The prevalence of AD has increased in the current rapidly aging …
Recent advance on carbamate-based cholinesterase inhibitors as potential multifunctional agents against Alzheimer's disease
Abstract Alzheimer's disease (AD), as the fourth leading cause of death among the elderly
worldwide, has brought enormous challenge to the society. Due to its extremely complex …
worldwide, has brought enormous challenge to the society. Due to its extremely complex …
Artificial intelligence and machine learning approaches using gene expression and variant data for personalized medicine
S Vadapalli, H Abdelhalim, S Zeeshan… - Briefings in …, 2022 - academic.oup.com
Precision medicine uses genetic, environmental and lifestyle factors to more accurately
diagnose and treat disease in specific groups of patients, and it is considered one of the …
diagnose and treat disease in specific groups of patients, and it is considered one of the …
[HTML][HTML] Effects of ketogenic diet on neuroinflammation in neurodegenerative diseases
Z Jiang, X Yin, M Wang, T Chen, Y Wang, Z Gao… - Aging and …, 2022 - ncbi.nlm.nih.gov
The ketogenic diet (KD) is a low-carbohydrate, high-fat and adequate-protein diet. As a diet
mimicking fasting, it triggers the production of ketone bodies (KBs) and brings the body into …
mimicking fasting, it triggers the production of ketone bodies (KBs) and brings the body into …
Antioxidant therapy in oxidative stress-induced neurodegenerative diseases: Role of nanoparticle-based drug delivery systems in clinical translation
Free radicals are formed as a part of normal metabolic activities but are neutralized by the
endogenous antioxidants present in cells/tissue, thus maintaining the redox balance. This …
endogenous antioxidants present in cells/tissue, thus maintaining the redox balance. This …
Targeting brain Renin-Angiotensin System for the prevention and treatment of Alzheimer's disease: Past, present and future
F Gouveia, A Camins, M Ettcheto, J Bicker… - Ageing Research …, 2022 - Elsevier
Alzheimer's disease (AD) is a well-known neurodegenerative disease characterized by the
presence of two main hallmarks–Tau hyperphosphorylation and Aβ deposits …
presence of two main hallmarks–Tau hyperphosphorylation and Aβ deposits …
Optical coherence tomography angiography in preclinical Alzheimer's disease
JA Van De Kreeke, HT Nguyen… - British Journal of …, 2020 - bjo.bmj.com
Background/aims As a protrusion from the brain, the retina might reflect the status of the
brain. Previous studies showed a decrease in vessel density and foveal avascular zone …
brain. Previous studies showed a decrease in vessel density and foveal avascular zone …
Toll‐Like Receptor 4: A Promising Therapeutic Target for Alzheimer's Disease
L Wu, X Xian, G Xu, Z Tan, F Dong… - Mediators of …, 2022 - Wiley Online Library
Alzheimer's disease (AD) is a progressive neurodegenerative disease that primarily
manifests as memory deficits and cognitive impairment and has created health challenges …
manifests as memory deficits and cognitive impairment and has created health challenges …
[HTML][HTML] MicroRNA-21 is a versatile regulator and potential treatment target in central nervous system disorders
X Bai, Z Bian - Frontiers in molecular neuroscience, 2022 - frontiersin.org
MicroRNAs (miRNAs) are a class of endogenous, non-coding, single-stranded RNAs with a
length of approximately 22 nucleotides that are found in eukaryotes. miRNAs are involved in …
length of approximately 22 nucleotides that are found in eukaryotes. miRNAs are involved in …
Nanocarrier mediated drug delivery as an impeccable therapeutic approach against Alzheimer's disease
For the past several years, dementia, is one of the predominantly observed groups of
symptoms in a geriatric population. Alzheimer's disease (AD) is a progressive memory …
symptoms in a geriatric population. Alzheimer's disease (AD) is a progressive memory …