Among the methods valuable for assessing spatial learning and memory impairments in
rodents, the Barnes maze (BM) task deserves special attention. It is based on the …

Recent literature has pointed to the existence of inflammasome-mediated inflammatory
pathways in central nervous system (CNS) disorders and associated changes in behavior …

Depression has been widely accepted as a major psychiatric disease affecting nearly 350
million people worldwide. Research focus is now shifting from studying the extrinsic and …

The adaptive responses of the body that maintain homeostasis in response to stressors can
be called “allostasis”, meaning “achieving stability through change”. Mediators produced by …

The immune and the detoxication systems of animals are characterized by allelic
polymorphisms, which underlie individual differences in ability to combat assaults from …

Background Alzheimer's disease (AD) is a neurodegenerative disorder characterized by
progressive loss of cognitive abilities and memory leading to dementia. Electroacupuncture …

Omega-3 fatty acids (ie, docosahexaenoic acid; DHA) regulate signal transduction and gene
expression, and protect neurons from death. In this study we examined the capacity of …

A diet high in saturated fat (HF) decreases levels of brain‐derived neurotrophic factor
(BDNF), to the extent that compromises neuroplasticity and cognitive function, and …

The biochemical mechanisms by which regular exercise significantly benefits health and
well being, including improved cognitive function, are not well understood. Four-week-old …

The hippocampal formation, which contains high levels of adrenal steroid receptors, is
vulnerable to insults such as stroke, seizures, and head trauma, and it is also sensitive and …