Mitochondrial dysfunction and therapeutic perspectives in cardiovascular diseases
Y Liu, Y Huang, C Xu, P An, Y Luo, L Jiao… - International journal of …, 2022 - mdpi.com
High mortality rates due to cardiovascular diseases (CVDs) have attracted worldwide
attention. It has been reported that mitochondrial dysfunction is one of the most important …
attention. It has been reported that mitochondrial dysfunction is one of the most important …
Mitochondrial transfer as a novel therapeutic approach in disease diagnosis and treatment
VJ Clemente-Suárez, A Martín-Rodríguez… - International Journal of …, 2023 - mdpi.com
Mitochondrial dysfunction is a hallmark of numerous diseases, including neurodegenerative
disorders, metabolic disorders, and cancer. Mitochondrial transfer, the transfer of …
disorders, metabolic disorders, and cancer. Mitochondrial transfer, the transfer of …
Enucleated oocyte donation: first for infertility treatment, then for mitochondrial diseases
G Pennings - Journal of Assisted Reproduction and Genetics, 2022 - Springer
There seems to be a consensus that enucleated oocyte donation (EOD) should only be used
to reduce the risk of having a child with mitochondrial disorders. However, this paper argues …
to reduce the risk of having a child with mitochondrial disorders. However, this paper argues …
Early evidence of the artificial transfer/transplant of mitochondria to oocytes and zygotes by MitoCeption
Oocytes may carry mutations in their mitochondrial DNA (mtDNA) which affect fertility and
embryo development leading to hereditary diseases or rejection. Mitochondrial replacement …
embryo development leading to hereditary diseases or rejection. Mitochondrial replacement …
Ultrastructural evaluation of the human oocyte at the germinal vesicle stage during the application of assisted reproductive technologies
MG Palmerini, S Antonouli, G Macchiarelli, S Cecconi… - Cells, 2022 - mdpi.com
After its discovery in 1825 by the physiologist JE Purkinje, the human germinal vesicle (GV)
attracted the interest of scientists. Discarded after laparotomy or laparoscopic ovum pick up …
attracted the interest of scientists. Discarded after laparotomy or laparoscopic ovum pick up …
The mitochondrial genome in aging and disease and the future of mitochondrial therapeutics
Mitochondria are intracellular organelles that utilize nutrients to generate energy in the form
of ATP by oxidative phosphorylation. Mitochondrial DNA (mtDNA) in humans is a 16,569 …
of ATP by oxidative phosphorylation. Mitochondrial DNA (mtDNA) in humans is a 16,569 …
[HTML][HTML] Mitochondrial Mutations Affect the Cardiovascular System during Aging and Oxidative Stress
AV Poznyak, VN Sukhorukov, MА Popov… - Gene …, 2023 - xiahepublishing.com
Mitochondria are one of the most crucial components of the cell. Aging has a critical impact
on mitochondria. Various studies have shown that the relationship between aging and …
on mitochondria. Various studies have shown that the relationship between aging and …
Emerging Multi-omic Approaches to the Molecular Diagnosis of Mitochondrial Disease and Available Strategies for Treatment and Prevention
F Khaghani, M Hemmati, M Ebrahimi… - Current …, 2024 - benthamdirect.com
Mitochondria are semi-autonomous organelles present in several copies within most cells in
the human body that are controlled by the precise collaboration of mitochondrial DNA …
the human body that are controlled by the precise collaboration of mitochondrial DNA …
Mito-TEMPO Improves the Meiosis Resumption and Mitochondrial Function of Vitrified Sheep Oocytes via the Recovery of Respiratory Chain Activity
X Zhao, A Dilixiati, L Zhang, A Aihemaiti, Y Song… - Animals, 2024 - mdpi.com
Simple Summary Vitrification causes oxidative stress and organelle damage in oocytes. The
results of this study reveal that Mito-TEMPO can efficaciously improve the oxidative stress …
results of this study reveal that Mito-TEMPO can efficaciously improve the oxidative stress …
The press-assisted fusion scheme significantly mitigates the quantity of HVJ-E required in mitochondrial replacement techniques
M Ma, S Jiang, W Jin, W Li, C Chen, K Lin… - …, 2024 - rep.bioscientifica.com
In brief: The impact of HVJ-E employed in mitochondrial replacement techniques (MRTs) on
embryonic development remains uncertain. This study has exhibited the influence of HVJ-E …
embryonic development remains uncertain. This study has exhibited the influence of HVJ-E …