The roundworm Caenorhabditis elegans has risen to the status of a top model organism for
biological research in the last fifty years. Among laboratory animals, this tiny nematode is …

Most studies in the field of ecology and evolution aiming to connect genotype to phenotype
rarely validate identified loci using functional tools. Recent developments in RNA …

Understanding how genotypes map onto phenotypes, fitness, and eventually organisms is
arguably the next major missing piece in a fully predictive theory of evolution. We refer to this …

To what extent can we predict how evolution occurs? Do genetic architectures and
developmental processes canalize the evolution of similar outcomes in a predictable …

Evolutionary developmental biology (evo‐devo) has undergone dramatic transformations
since its emergence as a distinct discipline. This paper aims to highlight the scope, power …

Abstract Schizophrenia's (SZ's) heritability and familial transmission have been known for
several decades; however, despite the clear evidence for a genetic component, it has been …

Studies of X chromosome evolution in various organisms have indicated that sex-biased
genes are nonrandomly distributed between the X and autosomes. Here, to extend these …

Abstract Developmental System Drift (DSD) is an evolutionary phenomenon whereby the
genetic underpinnings of a trait in a common ancestor diverge in descendant lineages even …

All genes interact with other genes, and their additive effects and epistatic interactions affect
an organism's phenotype and fitness. Recent theoretical and empirical work has advanced …

When diverse lineages repeatedly adapt to similar environmental challenges, the extent to
which the same genes are involved (gene reuse) varies across systems. We propose that …