SARS-CoV-2 infection drives an inflammatory response in human adipose tissue through infection of adipocytes and macrophages

GJ Martínez-Colón, K Ratnasiri, H Chen… - Science Translational …, 2022 - science.org
Obesity, characterized by chronic low-grade inflammation of the adipose tissue, is
associated with adverse coronavirus disease 2019 (COVID-19) outcomes, yet the …

B cell contribution to immunometabolic dysfunction and impaired immune responses in obesity

K Oleinika, B Slisere, D Catalán… - Clinical and …, 2022 - academic.oup.com
Obesity increases the risk of type 2 diabetes mellitus, cardiovascular disease, fatty liver
disease, and cancer. It is also linked with more severe complications from infections …

Inhibition of the mitochondrial pyruvate carrier simultaneously mitigates hyperinflammation and hyperglycemia in COVID-19

B Zhu, X Wei, H Narasimhan, W Qian, R Zhang… - Science …, 2023 - science.org
The relationship between diabetes and coronavirus disease 2019 (COVID-19) is
bidirectional: Although individuals with diabetes and high blood glucose (hyperglycemia) …

SARS-CoV-2 infects human adipose tissue and elicits an inflammatory response consistent with severe COVID-19

GJ Martínez-Colón, K Ratnasiri, H Chen, S Jiang… - bioRxiv, 2021 - biorxiv.org
The COVID-19 pandemic, caused by the viral pathogen SARS-CoV-2, has taken the lives of
millions of individuals around the world. Obesity is associated with adverse COVID-19 …

[HTML][HTML] Control of postprandial hyperglycemia by oral administration of the sea anemone mucus-derived α-amylase inhibitor (magnificamide)

O Sintsova, D Popkova, A Kalinovskii, A Rasin… - Biomedicine & …, 2023 - Elsevier
Diabetes mellitus is a serious threat to human health in both developed and developing
countries. Optimal disease control requires the use of a diet and a combination of several …

FABP4 as a Therapeutic Host Target Controlling SARS-CoV2 Infection

H Baazim, E Koyuncu, G Tuncman, MF Burak, L Merkel… - bioRxiv, 2024 - biorxiv.org
Host metabolic fitness is a critical determinant of infectious disease outcomes. Obesity,
aging, and other related metabolic disorders are recognized as high-risk disease modifiers …

Dissecting the Interrelationship between COVID‐19 and Diabetes Mellitus

PH Roham, JJ Kamath, S Sharma - Advanced Biology, 2023 - Wiley Online Library
COVID‐19 disease, caused by severe acute respiratory syndrome coronavirus 2 (SARS‐
CoV‐2), has led to enormous morbidity and mortality worldwide. After gaining entry into the …