Prior studies of anti-CD40 ligand (CD40L)–based immunosuppression demonstrated
effective prevention of islet and kidney allograft rejection in nonhuman primate models; …

Antibody‐mediated rejection (AMR) is a common cause of graft failure after pig‐to‐
nonhuman primate organ transplantation, even when the graft is from a pig with multiple …

Costimulation blockade (CoB)-based immunotherapy is a promising alternative to
immunosuppression for transplant recipients; however, the current limited understanding of …

In this issue of Transplantation, Tunbridge et al1 presented a timely overview on some of the
negative immune suppressive mechanisms, focusing specifically on dendritic and myeloid …

Xenotransplantation, the transplantation of organs or tissues between different species, has
emerged as a potential solution to address the organ shortage. Introduction of genetically …