Cross-reactive influenza-specific antibody-dependent cellular cytotoxicity antibodies in the absence of neutralizing antibodies

S Jegaskanda, ER Job, M Kramski, K Laurie… - The Journal of …, 2013 - journals.aai.org
A better understanding of immunity to influenza virus is needed to generate cross-protective
vaccines. Engagement of Ab-dependent cellular cytotoxicity (ADCC) Abs by NK cells leads …

What lies beneath: antibody dependent natural killer cell activation by antibodies to internal influenza virus proteins

HA Vanderven, F Ana-Sosa-Batiz, S Jegaskanda… - …, 2016 - thelancet.com
The conserved internal influenza proteins nucleoprotein (NP) and matrix 1 (M1) are well
characterised for T cell immunity, but whether they also elicit functional antibodies capable …

[HTML][HTML] Fc functional antibodies in humans with severe H7N9 and seasonal influenza

HA Vanderven, L Liu, F Ana-Sosa-Batiz, THO Nguyen… - JCI insight, 2017 - ncbi.nlm.nih.gov
BACKGROUND. Both seasonal and novel avian influenza viruses can result in severe
infections requiring hospitalization. Anti-influenza antibodies (Abs) with Fc-mediated effector …

Complete genome sequencing of Kaisodi virus isolated from ticks in India belonging to Phlebovirus genus, family Phenuiviridae

PD Yadav, DA Nyayanit, AM Shete, S Jain… - Ticks and tick-borne …, 2019 - Elsevier
An unknown virus was repeatedly isolated from hard tick (Haemaphysalis spinigera) during
a proactive arbovirus survey in ticks conducted in 1957, in India. The virus remained …

The anti-influenza virus effect of Phellinus igniarius extract

S Lee, JI Kim, J Heo, I Lee, S Park, MW Hwang… - Journal of …, 2013 - Springer
Herbal medicine has been used in the orient for thousands of years to treat large and small
ailments, including microbial infections. Although there are treatments for influenza virus …

[HTML][HTML] Understanding the treatment benefit of hyperimmune anti-influenza intravenous immunoglobulin (Flu-IVIG) for severe human influenza

HA Vanderven, DN Wentworth, WM Han, H Peck… - JCI insight, 2023 - ncbi.nlm.nih.gov
BACKGROUND Antibody-based therapies for respiratory viruses are of increasing
importance. The INSIGHT 006 trial administered anti-influenza hyperimmune intravenous …

Molecular and antigenic characterization of reassortant H3N2 viruses from turkeys with a unique constellation of pandemic H1N1 internal genes

Y Berhane, H Kehler, K Handel, T Hisanaga, W Xu… - PLoS …, 2012 - journals.plos.org
Triple reassortant (TR) H3N2 influenza viruses cause varying degrees of loss in egg
production in breeder turkeys. In this study we characterized TR H3N2 viruses isolated from …

Anti-influenza hyperimmune immunoglobulin enhances Fc-functional antibody immunity during human influenza infection

HA Vanderven, K Wragg… - The Journal of …, 2018 - academic.oup.com
Background New treatments for severe influenza are needed. Passive transfer of influenza-
specific hyperimmune pooled immunoglobulin (Flu-IVIG) boosts neutralizing antibody …

ArVirInd—a database of arboviral antigenic proteins from the Indian subcontinent

NM Atre, K Alagarasu, P Shil - PeerJ, 2022 - peerj.com
Background Studies on antigenic proteins for arboviruses are important for providing
diagnostics and vaccine development. India and its neighboring countries have a huge …

Genetic and antigenic typing of seasonal influenza virus breakthrough cases from a 2008-2009 vaccine efficacy trial

S Durviaux, J Treanor, J Beran, X Duval… - Clinical and Vaccine …, 2014 - Am Soc Microbiol
Estimations of the effectiveness of vaccines against seasonal influenza virus are guided by
comparisons of the antigenicities between influenza virus isolates from clinical breakthrough …