Many human conceptions are genetically abnormal and end in miscarriage, which is the
commonest complication of pregnancy. Recurrent miscarriage, the loss of three or more …

Background Progesterone, a female sex hormone, is known to induce secretory changes in
the lining of the uterus essential for successful implantation of a fertilized egg. It has been …

The majority of miscarriages are sporadic and most result from genetic causes that are
greatly influenced by maternal age. Recurrent pregnancy loss (RPL) is defined by two or …

Background Women who have had a spontaneous preterm delivery are at greatly increased
risk for preterm delivery in subsequent pregnancies. The results of several small trials have …

Objective: The purpose of this study was to evaluate the effect of prophylactic vaginal
progesterone in decreasing preterm birth rate in a high-risk population. Study design: A …

Human reproduction is extraordinarily wasteful. The reasons for this have taxed all of the
contributors to this book. As we move into the 21st century it is sobering to reflect on the fact …

Recurrent miscarriage (RM) is a heterogeneous condition. A large number of studies has
recently been published, yet many of them have conflicting conclusions. The various …

The aim of this prospective study was to analyze the characteristics of intrahepatic
cholestasis of pregnancy (ICP) in a French population. From 1989 to 1995 we studied 50 …

Objective Preterm birth is the leading cause of perinatal morbidity and mortality worldwide.
Treatment of preterm labor with tocolysis has not been successful in improving infant …

Two recently published metaanalyses of controlled trials of a wide variety of progestational
agents, used in pregnancy (Daya 1989; Goldstein et al. 1989), prompted this third …