A genital inflammatory profile contributes to the high risk of HIV acquisition in African
women. STIs and bacterial vaginosis are poorly managed in Africa and other developing …

HIV incidence continues to be unacceptably high in Eastern and Southern Africa, with
women disproportionately affected. An increased per-contact risk of HIV acquisition among …

Purpose Cervical cancer is the leading cause of cancer death among the 20 million women
with HIV worldwide. We sought to determine whether HIV infection affected survival in …

Background. Diagnosis and treatment of sexually transmitted infections (STIs) is a public
health priority, particularly in regions where the incidence of human immunodeficiency virus …

Women acquire human immunodeficiency virus (HIV) mainly through sexual intercourse.
However, low transmission rates per sexual act indicate that local immune mechanisms …

Recent iPrEx clinical trial results provided evidence that systemic preexposure prophylaxis
(PrEP) with emtricitabine (FTC) and tenofovir disoproxil fumarate (TDF) can partially prevent …

Mucosal immunity consists of innate and adaptive immune responses which can be
influenced by systemic immunity. Despite having been the subject of intensive studies, it is …

While the per-contact risk of sexual HIV transmission is relatively low, it is fourfold higher in
sub-Saharan Africa, and this may partly explain the major global disparities that exist in HIV …

Neoantigens unique to each patient's tumor can be recognized by autologous T cells
through their T-cell receptor (TCR) but the low frequency and/or terminal differentiation of …

Background. The biggest challenge in human immunodeficiency virus type 1 (HIV-1)
prevention in Africa is the high HIV-1 burden in young women. In macaques …