The prevalence of heart failure is on the rise and imposes a major health threat, in part, due
to the rapidly increased prevalence of overweight and obesity. To this point …

Overweight and obesity are well-established risk factors for most cardiovascular diseases
(CVD), including coronary heart disease (CHD), heart failure (HF), and atrial fibrillation …

Background: Lower leisure-time physical activity (LTPA) and higher body mass index (BMI)
are independently associated with risk of heart failure (HF). However, it is unclear if this …

Nonalcoholic fatty liver disease (NAFLD) and heart failure (HF) are obesity‐related
conditions with high cardiovascular mortality. Whether NAFLD is independently associated …

Aims We aimed to investigate whether the triglyceride–glucose (TyG) index, an easy-
calculated and reliable surrogate of insulin resistance, was associated with the development …

Background: Type 2 diabetes mellitus (T2DM) may alter cardiac structure and function, but
obesity, hypertension (HTN), or aging can induce similar abnormalities. Objectives: This …

Over the past 2 decades, the syndrome of heart failure with preserved ejection fraction
(HFpEF) received a lot of attention. 1–19 However, little therapeutic progress was made. 20 …

Background Non‐alcoholic fatty liver disease (NAFLD) is associated with high
cardiovascular morbidity/mortality, including heart failure. Abnormalities in left ventricular …

Background: Cumulative blood pressure (BP) exposure may adversely influence myocardial
function, predisposing individuals to heart failure later in life. Objectives: This study sought to …

Abstract The CARDIA (Coronary Artery Risk Development in Young Adults) study began in
1985 to 1986 with enrollment of 5,115 Black or White men and women ages 18 to 30 years …