Cryptococcus: from environmental saprophyte to global pathogen

RC May, NRH Stone, DL Wiesner, T Bicanic… - Nature Reviews …, 2016 - nature.com
Cryptococcosis is a globally distributed invasive fungal infection that is caused by species
within the genus Cryptococcus which presents substantial therapeutic challenges. Although …

Pulmonary cryptococcosis: a review of pathobiology and clinical aspects

F Setianingrum, R Rautemaa-Richardson… - Medical …, 2019 - academic.oup.com
Pulmonary cryptococcosis is an important opportunistic invasive mycosis in
immunocompromised patients, but it is also increasingly seen in immunocompetent patients …

Fungal infections in animals: a patchwork of different situations

S Seyedmousavi, SMG Bosco, S De Hoog… - Medical …, 2018 - academic.oup.com
The importance of fungal infections in both human and animals has increased over the last
decades. This article represents an overview of the different categories of fungal infections …

A global view on fungal infections in humans and animals: opportunistic infections and microsporidioses

S Gnat, D Łagowski, A Nowakiewicz… - Journal of Applied …, 2021 - academic.oup.com
After cardiovascular diseases, infectious diseases are the second most common cause of
death worldwide. Although these infections are caused mainly by viruses or bacteria, a …

Extracellular vesicles in fungi: past, present, and future perspectives

J Rizzo, ML Rodrigues, G Janbon - Frontiers in Cellular and Infection …, 2020 - frontiersin.org
Extracellular vesicles (EVs) have garnered much interest in the cell biology and biomedical
research fields. Many studies have reported the existence of EVs in all types of living cells …

[HTML][HTML] The role of mitochondrial dysfunction in age-related diseases

RK Lane, T Hilsabeck, SL Rea - Biochimica et Biophysica Acta (BBA) …, 2015 - Elsevier
The aging process is accompanied by the onset of disease and a general decline in
wellness. Insights into the aging process have revealed a number of cellular hallmarks of …

Pathogen-derived extracellular vesicles mediate virulence in the fatal human pathogen Cryptococcus gattii

E Bielska, MA Sisquella, M Aldeieg, C Birch… - Nature …, 2018 - nature.com
Abstract The Pacific Northwest outbreak of cryptococcosis, caused by a near-clonal lineage
of the fungal pathogen Cryptococcus gattii, represents the most significant cluster of life …

Extracellular vesicles in the fungi kingdom

M Liebana-Jordan, B Brotons, JM Falcon-Perez… - International Journal of …, 2021 - mdpi.com
Extracellular vesicles (EVs) are membranous, rounded vesicles released by prokaryotic and
eukaryotic cells in their normal and pathophysiological states. These vesicles form a network …

Division of labour in microorganisms: an evolutionary perspective

SA West, GA Cooper - Nature Reviews Microbiology, 2016 - nature.com
The division of labour, whereby individuals within a group specialize in certain tasks, has
long been appreciated as central to the evolution of complex biological societies. In recent …

Cryptococcus neoformans Intracellular Proliferation and Capsule Size Determines Early Macrophage Control of Infection

A Bojarczuk, KA Miller, R Hotham, A Lewis… - Scientific reports, 2016 - nature.com
Cryptococcus neoformans is a significant fungal pathogen of immunocompromised patients.
Many questions remain regarding the function of macrophages in normal clearance of …