Epithelial tight junctions define the paracellular permeability of the intestinal barrier.
Molecules can cross the tight junctions via two distinct size-selective and charge-selective …

The intestinal epithelial tight junction (TJ) barrier controls the paracellular permeation of
contents from the intestinal lumen into the intestinal tissue and systemic circulation. A …

The intestinal tract is the largest barrier between a person and the environment. In this role,
the intestinal tract is responsible not only for absorbing essential dietary nutrients, but also …

The ability of epithelial cells to organize through cell–cell adhesion into a functioning
epithelium serves the purpose of a tight epithelial protective barrier. Contacts between …

The intestinal tract is lined by a single layer of columnar epithelial cells that forms a dynamic,
permeable barrier allowing for selective absorption of nutrients, while restricting access to …

Epithelial tight junctions (TJs) are the key structures regulating paracellular trafficking of
macromolecules. The TJ is multi-protein complex that forms a selective permeable seal …

The microbiota, and the genes that comprise its microbiome, play key roles in human health.
Host-microbe interactions affect immunity, metabolism, development, and behavior, and …

The gastrointestinal epithelium forms the boundary between the body and external
environment. It effectively provides a selective permeable barrier that limits the permeation …

Background The intestinal mucosa is composed of a well-organized epithelium, acting as a
physical barrier to harmful luminal contents, while simultaneously ensuring absorption of …

Both alcoholic liver disease (ALD) and nonalcoholic fatty liver disease are characterized by
massive lipid accumulation in the liver accompanied by inflammation, fibrosis, cirrhosis, and …