Bile acids and their derivatives as potential modifiers of drug release and pharmacokinetic profiles

N Pavlović, S Goločorbin-Kon, M Ðanić… - Frontiers in …, 2018 - frontiersin.org
Bile acids have received considerable interest in the drug delivery research due to their
peculiar physicochemical properties and biocompatibility. The main advantage of bile acids …

Pharmacological applications of bile acids and their derivatives in the treatment of metabolic syndrome

M Ðanić, B Stanimirov, N Pavlović… - Frontiers in …, 2018 - frontiersin.org
Apart from well-known functions of bile acids in digestion and solubilization of lipophilic
nutrients and drugs in the small intestine, the emerging evidence from the past two decades …

Self-assembly of bile salts and their mixed aggregates as building blocks for smart aggregates

PY Parekh, VI Patel, MR Khimani, P Bahadur - Advances in Colloid and …, 2023 - Elsevier
The present communication offers a comprehensive overview of the self-assembly of bile
salts emphasizing their mixed smart aggregates with a variety of amphiphiles. Using an …

Application of bile acids in drug formulation and delivery

M Stojančević, N Pavlović, S Goločorbin-Kon… - Frontiers in Life …, 2013 - Taylor & Francis
Bile acids are naturally produced in humans and are known to provide human health
benefits through their endocrinological, microfloral, metabolic and other åffects that are still …

Semisynthetic bile acids: a new therapeutic option for metabolic syndrome

S Lazarević, M Đanić, S Goločorbin-Kon… - Pharmacological …, 2019 - Elsevier
Bile acids are endogenous emulsifiers synthesized from cholesterol having a peculiar
amphiphilic structure. Appreciation of their beneficial effects on human health, recognized …

Bile salts: unlocking the potential as bio-surfactant for enhanced drug absorption

PSA Chakravarthy, P Popli, RR Challa… - Journal of Nanoparticle …, 2024 - Springer
In the pursuit of developing new active ingredients for drug development, bile salts have
emerged as promising substances that can enhance absorption. Their unique properties …

Potential applications of gliclazide in treating type 1 diabetes mellitus: formulation with bile acids and probiotics

M Mikov, M Đanić, N Pavlović, B Stanimirov… - European Journal of …, 2018 - Springer
A major advancement in therapy of type 1 diabetes mellitus (T1DM) is the discovery of new
treatment which avoids and even replaces the absolute requirement for injected insulin. The …

Sodium cholate-enhanced polymeric micelle system for tumor-targeting delivery of paclitaxel

X Zhang, Y Wu, M Zhang, J Mao, Y Wu… - International Journal …, 2017 - Taylor & Francis
Purpose Polymeric micelles are attractive nanocarriers for tumor-targeted delivery of
paclitaxel (PTX). High antitumor efficacy and low toxicity require that PTX mainly …

Investigation of the effect of concurrently administered carvedilol, atorvastatin and bile salts on intestinal absorption of linagliptin

MA Embaby, GM El Maghraby… - Journal of Pharmacy …, 2023 - academic.oup.com
Objectives The aim of this work was to investigate the regional difference in linagliptin
intestinal membrane transport and to investigate the effects of carvedilol, atorvastatin and …

[PDF][PDF] SYNTHESIS, CHARACTERIZATION AND CYTOTOXICITY EVALUATION OF Ni (II), Cu (II) AND Zn (II) COMPLEXES WITH DEOXYCHOLATE LIGAND.

DC Culita, L Dyakova, G Marinescu, T Zhivkova… - …, 2021 - farmaciajournal.com
Trei noi complecși ai Ni (II), Cu (II) și Zn (II) cu anionul deoxicolat, de tipul M (DCA) 2· nH2O
(M= Cu (II) n= 4, M= Ni (II) n= 3 și M= Zn (II) n= 2), au fost sintetizați și caracterizați pe …