Exocrine pancreatic insufficiency (EPI) is a condition caused by reduced or inappropriate
secretion or activity of pancreatic juice and its digestive enzymes, pancreatic lipase in …

Patient acceptability of a medicinal product is a key aspect in the development and
prescribing of medicines. Children and older adults differ in many aspects from the other age …

Exocrine pancreatic insufficiency (EPI), an important cause of maldigestion and
malabsorption, results from primary pancreatic diseases or secondarily impaired exocrine …

Objective To evaluate acceptability of 2 mm solid dosage forms (mini-tablets) as an
alternative administration modality in young children in comparison with syrup. Study design …

Child‐appropriate drug formulations are a prerequisite of successful drug therapy in
children. Efficacy and safety must be given for the active pharmaceutical ingredient, but …

Oral pediatric formulations are either ready-to-use or require manipulation and multiuse or
single-use. Strong encouragement for preservative-free pediatric formulations has resulted …

Objectives The aim of this review was to map the currently available evidence on
acceptability of oral paediatric medicines to aid in the selection of suitable platform …

The selection and design of age-appropriate formulations intended for use in paediatric and
geriatric patients are dependent on multiple factors affecting patient acceptability, safety and …

The early diagnosis of pancreatic exocrine insufficiency (PEI) is hindered because many of
the functional diagnostic techniques used are expensive and require specialized facilities …

Background Most people with cystic fibrosis (CF)(80% to 90%) need pancreatic enzyme
replacement therapy (PERT) to prevent malnutrition. Enzyme preparations need to be taken …