Dementia prevention and treatment: a narrative review

DB Reuben, S Kremen, DT Maust - JAMA Internal Medicine, 2024 - jamanetwork.com
Importance Dementia affects 10% of those 65 years or older and 35% of those 90 years or
older, often with profound cognitive, behavioral, and functional consequences. As the baby …

Another Use for a Proven Drug: Experimental Evidence for the Potential of Artemisinin and Its Derivatives to Treat Alzheimer's Disease

E Kiss, S Kins, K Gorgas, KH Venczel Szakács… - International Journal of …, 2024 - mdpi.com
Plant-derived multitarget compounds may represent a promising therapeutic strategy for
multifactorial diseases, such as Alzheimer's disease (AD). Artemisinin and its derivatives …

IPECAD Modeling Workshop 2023 Cross-Comparison Challenge on Cost-Effectiveness Models in Alzheimer's Disease

R Handels, WL Herring, F Kamgar, S Aye, A Tate… - Value in Health, 2024 - Elsevier
Objectives Decision-analytic models assessing the value of emerging Alzheimer's disease
(AD) treatments are challenged by limited evidence on short-term trial outcomes and …

Public perceptions related to healthcare preparedness to anti-amyloid therapies for Alzheimer's Disease in Japan

K Sato, Y Niimi, R Ihara, A Iwata, K Suzuki… - Alzheimer's Research & …, 2024 - Springer
Background The approval of lecanemab, an anti-amyloid therapy for Alzheimer's disease
(AD), necessitates addressing healthcare preparedness for disease-modifying treatment …

New International Pharmaco-Economic Collaboration on Alzheimer's Disease (IPECAD) Open-Source Model Framework for the Health Technology Assessment of …

R Handels, WL Herring, S Grimm, A Sköldunger… - Value in Health, 2024 - Elsevier
Objectives Reimbursement decisions for new Alzheimer's disease (AD) treatments are
informed by economic evaluations. An open-source model with intuitive structure for model …

[PDF][PDF] Lecanemab Unveiled: Exploring Alzheimer's Treatment Advancements, Assessing Strengths, Limitations, and Its Therapeutic Landscape Position

VA Adepoju, OI Onyezue, S Jamil… - Biomedical and …, 2024 - researchgate.net
In the ever-evolving landscape of Alzheimer's treatment, lecanemab (Leqembi) has
emerged as a promising drug. Unlike conventional therapies that merely alleviate …

The efficacy and safety of lecanemab 10 mg/kg biweekly compared to a placebo in patients with Alzheimer's disease: a systematic review and meta-analysis of …

K Abdelazim, AA Allam, B Afifi, H Abdulazeem… - Neurological …, 2024 - Springer
Alzheimer's disease, prevalent in individuals aged 60 and above, constitutes most dementia
cases and significantly impairs memory and cognitive functions. With global Alzheimer's …

Knowledge and Attitudes toward New Disease-Modifying Treatments for Alzheimer's Disease among Nursing Home Directors

S Liang, BR Ott, J Tjia, KL Lapane, AC Rataj… - Journal of the American …, 2025 - Elsevier
Objectives Nursing home (NH) administrator perceptions regarding the utility of Alzheimer's
disease (AD) disease-modifying medications in NHs are important because many short and …

Health System Change for Alzheimer's Disease-Modifying Therapies in Canada: Beginning the Discussion

A Frank, Z Ismail, M Wilson, S Gauthier… - Canadian Journal of …, 2023 - cambridge.org
Alzheimer's disease (AD) is a neurodegenerative disorder that accounts for 60%–70% of
patients with dementia, and it is estimated that over one million Canadians will be living with …

Use of Lecanemab and Donanemab in the Canadian Healthcare System: Evidence, Challenges, and Areas for Future Research

EE Smith, N Phillips, HH Feldman, M Borrie, A Ganesh… - medRxiv, 2024 - medrxiv.org
Lecanemab and donanemab are monoclonal antibody therapies that remove amyloid-beta
from the brain. They are the first therapies that alter a fundamental mechanism, amyloid-beta …