Incomplete response to Anti-VEGF therapy in neovascular AMD: Exploring disease mechanisms and therapeutic opportunities
PS Mettu, MJ Allingham, SW Cousins - Progress in retinal and eye …, 2021 - Elsevier
Intravitreal anti-vascular endothelial growth factor (VEGF) drugs have revolutionized the
treatment of neovascular age-related macular degeneration (NVAMD). However, many …
treatment of neovascular age-related macular degeneration (NVAMD). However, many …
Visual impairment and mental health: unmet needs and treatment options
DL Demmin, SM Silverstein - Clinical Ophthalmology, 2020 - Taylor & Francis
Purpose An estimated 2.2 billion people are visually impaired worldwide. Given that age-
related vision loss is a primary cause of vision impairment, this number is projected to rise …
related vision loss is a primary cause of vision impairment, this number is projected to rise …
Prevalence of age-related macular degeneration in the US in 2019
DB Rein, JS Wittenborn, Z Burke-Conte… - JAMA …, 2022 - jamanetwork.com
Importance Age-related macular degeneration (AMD) is a leading cause of vision loss and
blindness. AMD prevalence has not been estimated for the US in over a decade and early …
blindness. AMD prevalence has not been estimated for the US in over a decade and early …
The impact of oxidative stress and inflammation on RPE degeneration in non-neovascular AMD
S Datta, M Cano, K Ebrahimi, L Wang… - Progress in retinal and …, 2017 - Elsevier
The retinal pigment epithelium (RPE) is a highly specialized, unique epithelial cell that
interacts with photoreceptors on its apical side and with Bruch's membrane and the …
interacts with photoreceptors on its apical side and with Bruch's membrane and the …
[PDF][PDF] Disparities in vision health and eye care
AR Elam, VL Tseng, TM Rodriguez, EV Mike… - Ophthalmology, 2022 - Elsevier
Conclusions As we continue on the journey of addressing disparities in eye care and vision
health, it is imperative to know where we currently stand to move our field forward in an …
health, it is imperative to know where we currently stand to move our field forward in an …
DeepSeeNet: a deep learning model for automated classification of patient-based age-related macular degeneration severity from color fundus photographs
Purpose In assessing the severity of age-related macular degeneration (AMD), the Age-
Related Eye Disease Study (AREDS) Simplified Severity Scale predicts the risk of …
Related Eye Disease Study (AREDS) Simplified Severity Scale predicts the risk of …
Comorbidity of fetal alcohol spectrum disorder: a systematic review and meta-analysis
S Popova, S Lange, K Shield, A Mihic, AE Chudley… - The Lancet, 2016 - thelancet.com
Background Fetal alcohol spectrum disorder (FASD) is related to many comorbidities
because of the permanent effects of prenatal alcohol exposure on the fetus. We aimed to …
because of the permanent effects of prenatal alcohol exposure on the fetus. We aimed to …
Causes of vision loss worldwide, 1990–2010: a systematic analysis
Background Data on causes of vision impairment and blindness are important for
development of public health policies, but comprehensive analysis of change in prevalence …
development of public health policies, but comprehensive analysis of change in prevalence …
Quantitative optical coherence tomography angiography of vascular abnormalities in the living human eye
Retinal vascular diseases are important causes of vision loss. A detailed evaluation of the
vascular abnormalities facilitates diagnosis and treatment in these diseases. Optical …
vascular abnormalities facilitates diagnosis and treatment in these diseases. Optical …
Visual impairment and blindness in adults in the United States: demographic and geographic variations from 2015 to 2050
R Varma, TS Vajaranant, B Burkemper, S Wu… - JAMA …, 2016 - jamanetwork.com
Importance The number of individuals with visual impairment (VI) and blindness is
increasing in the United States and around the globe as a result of shifting demographics …
increasing in the United States and around the globe as a result of shifting demographics …