Wound healing is a long‐term, multistage biological process that includes hemostasis,
inflammation, proliferation, and tissue remodeling and requires intelligent designs to provide …

Adipose-derived mesenchymal stem/stromal cells (ASCs) are an adult stem cell population
able to self-renew and differentiate into numerous cell lineages. ASCs provide a promising …

Engineering therapeutic angiogenesis in impaired tissues is critical for chronic wound
healing. Materials can be engineered to deliver specific biological cues that enhance …

Soft tissue defects are a common clinical challenge mostly caused by trauma, congenital
anomalies and oncological surgery. Current soft tissue reconstruction options include …

Chronic wounds, especially diabetic wounds, involve abnormally long inflammatory periods
due to their pathological microenvironment of high reactive oxygen species (ROS) levels …

Hydrogels provide a plethora of advantages to biomedical treatments due to their highly
hydrophilic nature and tissue-like mechanical properties. Additionally, the numerous and …

Circular RNA (circRNA), bioactive ion and nitric oxide (NO) are beneficial to myocardial
repair after myocardial infarction (MI); however, to achieve efficient intervention of circRNA …

Mesenchymal stem cells (MSCs) have drawn lots of attention as gold standard stem cells in
fundamental and clinical researches during the last 20 years. Due to their tissue and …

Wound repair, particularly chronic nonhealing wound repair, is a global health issue that
affects millions of people worldwide. As an effective and safe therapeutic reagent, gas …

In the field of orthopaedics, bone defects caused by severe trauma, infection, tumor
resection, and skeletal abnormalities are very common. However, due to the lengthy and …