On the neuroprotective effects of naringenin: pharmacological targets, signaling pathways, molecular mechanisms, and clinical perspective

Z Nouri, S Fakhri, FF El-Senduny, N Sanadgol… - Biomolecules, 2019 - mdpi.com
As a group of progressive, chronic, and disabling disorders, neurodegenerative diseases
(NDs) affect millions of people worldwide, and are on the rise. NDs are known as the …

Naringenin: its chemistry and roles in neuroprotection

AV Atoki, PM Aja, TS Shinkafi, EN Ondari… - Nutritional …, 2024 - Taylor & Francis
According to epidemiological research, as the population ages, neurological illnesses are
becoming a bigger issue. Despite improvements in the treatment of these diseases, there …

Identification of potential biogenic chalcones against antibiotic resistant efflux pump (AcrB) via computational study

S Rathod, S Dey, S Pawar, R Dhavale… - Journal of …, 2024 - Taylor & Francis
The cases of bacterial multidrug resistance are increasing every year and becoming a
serious concern for human health. Multidrug efflux pumps are key players in the formation of …

Exploring biogenic chalcones as DprE1 inhibitors for antitubercular activity via in silico approach

S Rathod, P Chavan, D Mahuli, S Rochlani… - Journal of Molecular …, 2023 - Springer
Cases of drug-resistant tuberculosis (TB) have increased worldwide in the last few years,
and it is a major threat to global TB control strategies and the human population …

Identification of hits as anti-obesity agents against human pancreatic lipase via docking, drug-likeness, in-silico ADME(T), pharmacophore, DFT, molecular dynamics …

S Choudhari, SK Patil, S Rathod - Journal of Biomolecular …, 2023 - Taylor & Francis
Obesity, characterized by excessive fat accumulation, is a major health concern. Inhibition of
human pancreatic lipase, an enzyme involved in fat digestion, offers a potential strategy for …

Hypoglycemia causes dysregulation of Neuregulin 1, ErbB receptors, Ki67 in cerebellum and brainstem during diabetes: Implications in motor function

M Joshi, A Krishnakumar - Behavioural Brain Research, 2019 - Elsevier
Hypoglycemia induced brain injury poses a major setback to optimal blood glucose
regulation during diabetes. It causes irreversible injury in several brain regions culminating …

[PDF][PDF] DESIGN AND SYNTHESIS OF NEW ULK1/2 INHIBITOR AS ANTICANCER AGENT

SP Salim, MNNM Pharm - gtusitecirculars.s3.amazonaws.com
Autophagy initiation kinase 1 and 2 (also known as ULK1/2 in humans) is a protein kinase
that plays a key role in the initiation of the autophagy process. Autophagy is a cellular …