Medicinal plants in Brazil: Pharmacological studies, drug discovery, challenges and perspectives

RC Dutra, MM Campos, ARS Santos… - Pharmacological research, 2016 - Elsevier
This review article focuses on pre-clinical and clinical studies with some selected Brazilian
medicinal plants in different areas of interest, conducted by research groups in Brazil and …

Hyperoside: a review of its structure, synthesis, pharmacology, pharmacokinetics and toxicity

S Xu, S Chen, W Xia, H Sui, X Fu - Molecules, 2022 - mdpi.com
Hyperoside is an active ingredient in plants, such as Hypericum monogynum in
Hypericaceae, Crataegus pinnatifida in Rosaceae and Polygonum aviculare in …

Antidepressant Potential of Quercetin and its Glycoside Derivatives: A Comprehensive Review and Update

S Chen, Y Tang, Y Gao, K Nie, H Wang, H Su… - Frontiers in …, 2022 - frontiersin.org
Depression is a global health problem with growing prevalence rates and serious impacts
on the daily life of patients. However, the side effects of currently used antidepressants …

Antidepressant flavonoids and their relationship with oxidative stress

L Hritcu, R Ionita, PA Postu, GK Gupta… - Oxidative Medicine …, 2017 - Wiley Online Library
Depression is a serious disorder that affects hundreds of millions of people around the world
and causes poor quality of life, problem behaviors, and limitations in activities of daily living …

Hypericum genus as a natural source for biologically active compounds

GI Caldeira, LP Gouveia, R Serrano, OD Silva - Plants, 2022 - mdpi.com
Hypericum L. genus plants are distributed worldwide, with numerous species identified
throughout all continents, except Antarctica. These plant species are currently used in …

Antiosteoporotic compounds from seeds of Cuscuta chinensis

L Yang, Q Chen, F Wang, G Zhang - Journal of ethnopharmacology, 2011 - Elsevier
Ethnopharmacological relevance The seeds of Cuscuta chinensis (Tu–Si–Zi, TSZ) have
long been used for the treatment of osteoporosis in China and some Asian countries. The …

Emerging role of flavonoids as the treatment of depression

A Pannu, PC Sharma, VK Thakur, RK Goyal - Biomolecules, 2021 - mdpi.com
Depression is one of the most frequently observed psychological disorders, affecting
thoughts, feelings, behavior and a sense of well-being in person. As per the WHO, it is …

Medicinal plants in the treatment of depression: Evidence from preclinical studies

I Moragrega, JL Ríos - Planta medica, 2021 - thieme-connect.com
Medicinal plants and their extracts are natural remedies with enormous potential for treating
various diseases, including depression and anxiety. In the case of depression, hundreds of …

[HTML][HTML] Hyperoside protects against cyclophosphamide induced ovarian damage and reduced fertility by suppressing HIF-1α/BNIP3-mediated autophagy

F Zhu, J Gao, F Zeng, Y Lai, X Ruan, G Deng - Biomedicine & …, 2022 - Elsevier
Ovarian damage and infertility are the main side effects of chemotherapy for women of
childbearing age with cancer. The main objective of this study was to investigate the …

Flavonols in action: Targeting oxidative stress and neuroinflammation in major depressive disorder

M Jazvinšćak Jembrek, N Oršolić, D Karlović… - International journal of …, 2023 - mdpi.com
Major depressive disorder is one of the most common mental illnesses that highly impairs
quality of life. Pharmacological interventions are mainly focused on altered monoamine …