Bee venom: an updating review of its bioactive molecules and its health applications
M Carpena, B Nuñez-Estevez, A Soria-Lopez… - Nutrients, 2020 - mdpi.com
Bee venom (BV) is usually associated with pain since, when humans are stung by bees,
local inflammation and even an allergic reaction can be produced. BV has been traditionally …
local inflammation and even an allergic reaction can be produced. BV has been traditionally …
Three valuable peptides from bee and wasp venoms for therapeutic and biotechnological use: melittin, apamin and mastoparan
While knowledge of the composition and mode of action of bee and wasp venoms dates
back 50 years, the therapeutic value of these toxins remains relatively unexploded. The …
back 50 years, the therapeutic value of these toxins remains relatively unexploded. The …
Small-Conductance Ca2+-Activated K+ Channels: Form and Function
JP Adelman, J Maylie, P Sah - Annual review of physiology, 2012 - annualreviews.org
Small-conductance Ca2+-activated K+ channels (SK channels) are widely expressed
throughout the central nervous system. These channels are activated solely by increases in …
throughout the central nervous system. These channels are activated solely by increases in …
Bee updated: current knowledge on bee venom and bee envenoming therapy
Honey bees can be found all around the world and fulfill key pollination roles within their
natural ecosystems, as well as in agriculture. Most species are typically docile, and most …
natural ecosystems, as well as in agriculture. Most species are typically docile, and most …
Insect natural products and processes: new treatments for human disease
In this overview, some of the more significant recent developments in bioengineering natural
products from insects with use or potential use in modern medicine are described, as well as …
products from insects with use or potential use in modern medicine are described, as well as …
Potassium channels in Parkinson's disease: potential roles in its pathogenesis and innovative molecular targets for treatment
Parkinson's disease (PD) is a neurodegenerative disorder characterized by selective loss of
dopaminergic neurons in the substantia nigra pars compacta (SNpc) region of the midbrain …
dopaminergic neurons in the substantia nigra pars compacta (SNpc) region of the midbrain …
International union of basic and clinical pharmacology. C. Nomenclature and properties of calcium-activated and sodium-activated potassium channels
LK Kaczmarek, RW Aldrich, KG Chandy… - Pharmacological …, 2017 - ASPET
A subset of potassium channels is regulated primarily by changes in the cytoplasmic
concentration of ions, including calcium, sodium, chloride, and protons. The eight members …
concentration of ions, including calcium, sodium, chloride, and protons. The eight members …
Pharmacological alternatives for the treatment of neurodegenerative disorders: Wasp and bee venoms and their components as new neuroactive tools
Neurodegenerative diseases are relentlessly progressive, severely impacting affected
patients, families and society as a whole. Increased life expectancy has made these …
patients, families and society as a whole. Increased life expectancy has made these …
Pharmacology of small-and intermediate-conductance calcium-activated potassium channels
BM Brown, H Shim, P Christophersen… - Annual review of …, 2020 - annualreviews.org
The three small-conductance calcium-activated potassium (KCa2) channels and the related
intermediate-conductance KCa3. 1 channel are voltage-independent K+ channels that …
intermediate-conductance KCa3. 1 channel are voltage-independent K+ channels that …
Therapeutic effects of apamin as a bee venom component for non-neoplastic disease
H Gu, SM Han, KK Park - Toxins, 2020 - mdpi.com
Bee venom is a natural toxin produced by honeybees and plays an important role in
defending bee colonies. Bee venom has several kinds of peptides, including melittin …
defending bee colonies. Bee venom has several kinds of peptides, including melittin …