Global phylogeography of Mycobacterium tuberculosis and implications for tuberculosis product development

S Gagneux, PM Small - The Lancet infectious diseases, 2007 - thelancet.com
New tools for controlling tuberculosis are urgently needed. Despite our emerging
understanding of the biogeography of Mycobacterium tuberculosis, the implications for …

Classification, identification, and clinical significance of Haemophilus and Aggregatibacter species with host specificity for humans

N Nørskov-Lauritsen - Clinical microbiology reviews, 2014 - Am Soc Microbiol
The aim of this review is to provide a comprehensive update on the current classification and
identification of Haemophilus and Aggregatibacter species with exclusive or predominant …

How clonal are bacteria?

JM Smith, NH Smith, M O'Rourke… - Proceedings of the …, 1993 - National Acad Sciences
Data from multilocus enzyme electrophoresis of bacterial populations were analyzed using a
statistical test designed to detect associations between genes at different loci. Some species …

Traces of Human Migrations in Helicobacter pylori Populations

D Falush, T Wirth, B Linz, JK Pritchard, M Stephens… - science, 2003 - science.org
Helicobacter pylori, a chronic gastric pathogen of human beings, can be divided into seven
populations and subpopulations with distinct geographical distributions. These modern …

Variable host–pathogen compatibility in Mycobacterium tuberculosis

S Gagneux, K DeRiemer, T Van… - Proceedings of the …, 2006 - National Acad Sciences
Mycobacterium tuberculosis remains a major cause of morbidity and mortality worldwide.
Studies have reported human pathogens to have geographically structured population …

Geographic barriers isolate endemic populations of hyperthermophilic archaea

RJ Whitaker, DW Grogan, JW Taylor - Science, 2003 - science.org
Barriers to dispersal between populations allow them to diverge through local adaptation or
random genetic drift. High-resolution multilocus sequence analysis revealed that, on a …

Imperfect vaccines and the evolution of pathogen virulence

S Gandon, MJ Mackinnon, S Nee, AF Read - Nature, 2001 - nature.com
Vaccines rarely provide full protection from disease. Nevertheless, partially effective
(imperfect) vaccines may be used to protect both individuals and whole populations,,. We …

PCR for capsular typing of Haemophilus influenzae

TJ Falla, DW Crook, LN Brophy, D Maskell… - Journal of clinical …, 1994 - Am Soc Microbiol
A PCR method for the unequivocal assignment of Haemophilus influenzae capsular type
(types a to f) was developed. PCR primers were designed from capsule type-specific DNA …

Human IgG Fc receptor heterogeneity: molecular aspects and clinical implications

JGJ van de Winkel, PJA Capel - Immunology today, 1993 - cell.com
Some of the most important structures in the immune system are the receptors for the Fc
domain of antibodies. These provide an essential feedback between the humoral and the …

Application of molecular techniques to the study of hospital infection

A Singh, RV Goering, S Simjee, SL Foley… - Clinical microbiology …, 2006 - Am Soc Microbiol
Nosocomial infections are an important source of morbidity and mortality in hospital settings,
afflicting an estimated 2 million patients in United States each year. This number represents …