Advances in leprosy immunology and the field application: a gap to bridge
VNB De Souza, AM Iyer, DA Lammas, B Naafs… - Clinics in …, 2016 - Elsevier
Advances concerning the hosts' immune response to Mycobacterium leprae infection have
focused on elucidating the immune pathomechanisms involved, with the hope that predictive …
focused on elucidating the immune pathomechanisms involved, with the hope that predictive …
Genotyping and drug resistance patterns of M. tuberculosis strains in Pakistan
Background The incidence of tuberculosis in Pakistan is 181/100,000 population. However,
information about transmission and geographical prevalence of Mycobacterium tuberculosis …
information about transmission and geographical prevalence of Mycobacterium tuberculosis …
PGL I expression in live bacteria allows activation of a CD206/PPARγ cross-talk that may contribute to successful Mycobacterium leprae colonization of peripheral …
CC Diaz Acosta, AA Dias, TLSA Rosa… - PLoS …, 2018 - journals.plos.org
Mycobacterium leprae, an obligate intracellular bacillus, infects Schwann cells (SCs),
leading to peripheral nerve damage, the most severe leprosy symptom. In the present study …
leading to peripheral nerve damage, the most severe leprosy symptom. In the present study …
Expression of M. tuberculosis-induced suppressor of cytokine signaling (SOCS) 1, SOCS3, FoxP3 and secretion of IL-6 associates with differing clinical severity of …
Background Appropriate immune activation of T cells and macrophages is central for the
control of Mycobacterium tuberculosis infections. IFN-γ stimulated responses are lowered in …
control of Mycobacterium tuberculosis infections. IFN-γ stimulated responses are lowered in …
Serum Th17 cytokines in leprosy: correlation with circulating CD4+ CD25highFoxP3+ T-regs cells, as well as down regulatory cytokines
EAS Attia, M Abdallah, E El-Khateeb, AA Saad… - Archives of …, 2014 - Springer
Leprosy is not only a bacteriological disease but also an immunological disease, in which T
helper17 and CD4+ CD25 high FoxP3+ regulatory T cells (T-regs), among others, may play …
helper17 and CD4+ CD25 high FoxP3+ regulatory T cells (T-regs), among others, may play …
M. leprae inhibits apoptosis in THP-1 cells by downregulation of Bad and Bak and upregulation of Mcl-1 gene expression
Z Hasan, M Ashraf, A Tayyebi, R Hussain - BMC microbiology, 2006 - Springer
Abstract Background Virulent Mycobacterium leprae interfere with host defense mechanisms
such as cytokine activation and apoptosis. The mitochondrial pathway of apoptosis is …
such as cytokine activation and apoptosis. The mitochondrial pathway of apoptosis is …
Elevated Serum CCL2 Concomitant with a Reduced Mycobacterium‐Induced Response Leads to Disease Dissemination in Leprosy
Mycobacterium leprae and Mycobacterium tuberculosis are successful intracellular
pathogens which downregulate host immune responses. T‐cell interferon‐γ (IFNγ) and …
pathogens which downregulate host immune responses. T‐cell interferon‐γ (IFNγ) and …
Reduced TNF-α and IFN-γ responses to Central Asian strain 1 and Beijing isolates of Mycobacterium tuberculosis in comparison with H37Rv strain
M Tanveer, Z Hasan, A Kanji… - Transactions of the …, 2009 - academic.oup.com
Pakistan ranks eighth in terms of tuberculosis burden worldwide, with an incidence of
181/100 000. The predominant genotypes of Mycobacterium tuberculosis are reported to be …
181/100 000. The predominant genotypes of Mycobacterium tuberculosis are reported to be …
Elevated ex vivo monocyte chemotactic protein-1 (CCL2) in pulmonary as compared with extra-pulmonary tuberculosis
Background Tuberculosis causes 3 million deaths annually. The most common site of
tuberculosis is pulmonary however; extra-pulmonary forms of the disease also remain …
tuberculosis is pulmonary however; extra-pulmonary forms of the disease also remain …
[HTML][HTML] IL-10 gene promoter polymorphisms and leprosy in a Colombian population sample
Abstract CARDONA-CASTRO, Nora; SANCHEZ-JIMENEZ, Miryam; ROJAS, Winston and
BEDOYA-BERRIO, Gabriel. IL-10 gene promoter polymorphisms and leprosy in a …
BEDOYA-BERRIO, Gabriel. IL-10 gene promoter polymorphisms and leprosy in a …