A large body of experimental evidence suggests that neuroinflammation is a key
pathological event triggering and perpetuating the neurodegenerative process associated …

The etiology of most neurodegenerative disorders is multifactorial and consists of an
interaction between environmental factors and genetic predisposition. The role of pesticide …

Microglia are resident cells of the brain involved in regulatory processes critical for
development, maintenance of the neural environment, injury and repair. They belong to the …

Microglia are the main immune cells in the brain, playing a role in both physiological and
pathological conditions. Microglial involvement in neurodegenerative diseases is well …

Approximately 1.7 million people in the United States annually experience a traumatic brain
injury (TBI). 1 The number of unreported head injuries is much higher. Sports-related head …

Errors in neuron-microglial interaction are known to lead to microglial phagocytosis of live
neurons and excessive neuronal loss, potentially yielding poorer clinical outcomes. Factors …

Unconjugated hyperbilirubinemia is a common condition in the first week of postnatal life.
Although generally harmless, some neonates may develop very high levels of unconjugated …

Multiple sclerosis (MS) is often associated with co-morbid behavioural and cognitive
impairments; however the presence of these symptoms does not necessarily correlate with …

Laboratory studies involving repeated exposure to paraquat (PQ) in different animal models
can induce many of the pathological features of Parkinson's disease (PD), such as the loss …

Parkinson′ s disease (PD) is a common neurodegenerative disorder characterized by the
progressive loss of dopaminergic (DA) neurons in the substantia nigra. Although the exact …