Neuraxial cytokines in pain states
G Gonçalves dos Santos, L Delay, TL Yaksh… - Frontiers in …, 2020 - frontiersin.org
A high-intensity potentially tissue-injuring stimulus generates a homotopic response to
escape the stimulus and is associated with an affective phenotype considered to represent …
escape the stimulus and is associated with an affective phenotype considered to represent …
Crosstalk between vascular endothelial growth factor, notch, and transforming growth factor-β in vascular morphogenesis
MT Holderfield, CCW Hughes - Circulation research, 2008 - Am Heart Assoc
Vascular morphogenesis encompasses a temporally regulated set of morphological
changes that endothelial cells undergo to generate a network of interconnected tubules …
changes that endothelial cells undergo to generate a network of interconnected tubules …
Dysregulated YAP1/TAZ and TGF-β signaling mediate hepatocarcinogenesis in Mob1a/1b-deficient mice
M Nishio, K Sugimachi, H Goto… - Proceedings of the …, 2016 - National Acad Sciences
Mps One Binder Kinase Activator (MOB) 1A/1B are core components of the Hippo pathway
that coactivate large tumor suppressor homolog (LATS) kinases. Mob1a/1b double …
that coactivate large tumor suppressor homolog (LATS) kinases. Mob1a/1b double …
Insulin signaling and the regulation of insect diapause
C Sim, DL Denlinger - Frontiers in physiology, 2013 - frontiersin.org
A rich chapter in the history of insect endocrinology has focused on hormonal control of
diapause, especially the major roles played by juvenile hormones (JHs), ecdysteroids, and …
diapause, especially the major roles played by juvenile hormones (JHs), ecdysteroids, and …
[HTML][HTML] Spectrins: a structural platform for stabilization and activation of membrane channels, receptors and transporters
B Machnicka, A Czogalla… - … et Biophysica Acta (BBA …, 2014 - Elsevier
This review focuses on structure and functions of spectrin as a major component of the
membrane skeleton. Recent advances on spectrin function as an interface for signal …
membrane skeleton. Recent advances on spectrin function as an interface for signal …
Mechanisms and pathways of growth failure in primordial dwarfism
A Klingseisen, AP Jackson - Genes & development, 2011 - genesdev.cshlp.org
The greatest difference between species is size; however, the developmental mechanisms
determining organism growth remain poorly understood. Primordial dwarfism is a group of …
determining organism growth remain poorly understood. Primordial dwarfism is a group of …
Ppp1r15 gene knockout reveals an essential role for translation initiation factor 2 alpha (eIF2α) dephosphorylation in mammalian development
HP Harding, Y Zhang, D Scheuner… - Proceedings of the …, 2009 - National Acad Sciences
Diverse cellular stress responses are linked to phosphorylation of serine 51 on the alpha
subunit of translation initiation factor 2. The resultant attenuation of protein synthesis and …
subunit of translation initiation factor 2. The resultant attenuation of protein synthesis and …
TGF-β2 suppresses macrophage cytokine production and mucosal inflammatory responses in the developing intestine
A Maheshwari, DR Kelly, T Nicola, N Ambalavanan… - Gastroenterology, 2011 - Elsevier
BACKGROUND & AIMS: Premature neonates are predisposed to necrotizing enterocolitis
(NEC), an idiopathic, inflammatory bowel necrosis. We investigated whether NEC occurs in …
(NEC), an idiopathic, inflammatory bowel necrosis. We investigated whether NEC occurs in …
Structure of the bone morphogenetic protein receptor ALK2 and implications for fibrodysplasia ossificans progressiva
A Chaikuad, I Alfano, G Kerr, CE Sanvitale… - Journal of Biological …, 2012 - ASBMB
Bone morphogenetic protein (BMP) receptor kinases are tightly regulated to control
development and tissue homeostasis. Mutant receptor kinase domains escape regulation …
development and tissue homeostasis. Mutant receptor kinase domains escape regulation …
Dorsomorphin, a selective small molecule inhibitor of BMP signaling, promotes cardiomyogenesis in embryonic stem cells
Background Pluripotent embryonic stem (ES) cells, which have the capacity to give rise to all
tissue types in the body, show great promise as a versatile source of cells for regenerative …
tissue types in the body, show great promise as a versatile source of cells for regenerative …