Mortality-related risk factors of COVID-19: a systematic review and meta-analysis of 42 studies and 423,117 patients
Background Mortality rates of coronavirus disease-2019 (COVID-19) continue to rise across
the world. The impact of several risk factors on coronavirus mortality has been previously …
the world. The impact of several risk factors on coronavirus mortality has been previously …
Sex differences in immunity to viral infections
H Jacobsen, SL Klein - Frontiers in immunology, 2021 - frontiersin.org
The ongoing COVID-19 pandemic has increased awareness about sex-specific differences
in immunity and outcomes following SARS-CoV-2 infection. Strong evidence of a male bias …
in immunity and outcomes following SARS-CoV-2 infection. Strong evidence of a male bias …
Male sex identified by global COVID-19 meta-analysis as a risk factor for death and ITU admission
H Peckham, NM de Gruijter, C Raine… - Nature …, 2020 - nature.com
Anecdotal evidence suggests that Coronavirus disease 2019 (COVID-19), caused by the
coronavirus SARS-CoV-2, exhibits differences in morbidity and mortality between sexes …
coronavirus SARS-CoV-2, exhibits differences in morbidity and mortality between sexes …
Sex hormone signaling and regulation of immune function
Immune responses to antigens, including innocuous, self, tumor, microbial, and vaccine
antigens, differ between males and females. The quest to uncover the mechanisms for …
antigens, differ between males and females. The quest to uncover the mechanisms for …
Sexual-dimorphism in human immune system aging
EJ Márquez, C Chung, R Marches, RJ Rossi… - Nature …, 2020 - nature.com
Differences in immune function and responses contribute to health-and life-span disparities
between sexes. However, the role of sex in immune system aging is not well understood …
between sexes. However, the role of sex in immune system aging is not well understood …
Effects of sex and aging on the immune cell landscape as assessed by single-cell transcriptomic analysis
Z Huang, B Chen, X Liu, H Li, L Xie… - Proceedings of the …, 2021 - National Acad Sciences
Sex and aging influence the human immune system, resulting in disparate responses to
infection, autoimmunity, and cancer. However, the impact of sex and aging on the immune …
infection, autoimmunity, and cancer. However, the impact of sex and aging on the immune …
Cancer immunotherapy efficacy and patients' sex: a systematic review and meta-analysis
Background Despite the acknowledged sex-related dimorphism in immune system
response, little is known about the effect of patients' sex on the efficacy of immune …
response, little is known about the effect of patients' sex on the efficacy of immune …
[HTML][HTML] Sex differences in immune responses
SL Klein, KL Flanagan - Nature Reviews Immunology, 2016 - nature.com
Males and females differ in their immunological responses to foreign and self-antigens and
show distinctions in innate and adaptive immune responses. Certain immunological sex …
show distinctions in innate and adaptive immune responses. Certain immunological sex …
Sex differences in cancer mechanisms
JB Rubin, JS Lagas, L Broestl, J Sponagel… - Biology of sex …, 2020 - Springer
We now know that cancer is many different diseases, with great variation even within a
single histological subtype. With the current emphasis on developing personalized …
single histological subtype. With the current emphasis on developing personalized …
Sex and gender differences in bacterial infections
SP Dias, MC Brouwer, D van de Beek - Infection and Immunity, 2022 - Am Soc Microbiol
There is a growing awareness of the importance of sex and gender in medicine and
research. Women typically have stronger immune responses to self and foreign antigens …
research. Women typically have stronger immune responses to self and foreign antigens …