Influence of the nutritional status and oxidative stress in the desaturation and elongation of n-3 and n-6 polyunsaturated fatty acids: Impact on non-alcoholic fatty liver …

LA Videla, MC Hernandez-Rodas, AH Metherel… - … and Essential Fatty …, 2022 - Elsevier
Polyunsaturated fatty acids (PUFA) play essential roles in cell membrane structure and
physiological processes including signal transduction, cellular metabolism and tissue …

Pathways of polyunsaturated fatty acid utilization: implications for brain function in neuropsychiatric health and disease

JJ Liu, P Green, JJ Mann, SI Rapoport, ME Sublette - Brain research, 2015 - Elsevier
Essential polyunsaturated fatty acids (PUFAs) have profound effects on brain development
and function. Abnormalities of PUFA status have been implicated in neuropsychiatric …

Personalized immunotherapy against several neuronal and brain tumors

S Kuttruff-coqui, T Weinschenk, J Fritsche… - US Patent …, 2021 - Google Patents
2014-11-12 Assigned to IMMATICS BIOTECHNOLOGIES GMBH reassignment IMMATICS
BIOTECHNOLOGIES GMBH ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT …

Fatty acid regulation of gene transcription

DB Jump - Critical reviews in clinical laboratory sciences, 2004 - Taylor & Francis
Dietary fat has a dual role in human physiology: a) it functions as a source of energy and
structural components for cells; b) it functions as a regulator of gene expression that impacts …

Delta-5 and delta-6 desaturases: crucial enzymes in polyunsaturated fatty acid-related pathways with pleiotropic influences in health and disease

F Tosi, F Sartori, P Guarini, O Olivieri… - Oxidative stress and …, 2014 - Springer
Polyunsaturated fatty acids (PUFA) play pleiotropic and crucial roles in biological systems.
Both blood and tissue levels of PUFA are influenced not only by diet, but to a large extent …

Single nucleotide polymorphisms in the FADS gene cluster are associated with delta-5 and delta-6 desaturase activities estimated by serum fatty acid ratios [S]

S Bokor, J Dumont, A Spinneker… - Journal of lipid …, 2010 - ASBMB
Genetic variability in the FADS1-FADS2 gene cluster [encoding delta-5 (D5D) and delta-6
(D6D) desaturases] has been associated with plasma long-chain PUFA (LCPUFA) and lipid …

[图书][B] Fat detection: taste, texture, and post ingestive effects

JP Montmayeur, J Le Coutre - 2009 - taylorfrancis.com
Presents the State-of-the-Art in Fat Taste TransductionA bite of cheese, a few potato chips, a
delectable piece of bacon-a small taste of high-fat foods often draws you back for more. But …

[HTML][HTML] α-Linolenic acid, Δ6-desaturase gene polymorphism, and the risk of nonfatal myocardial infarction

A Baylin, E Ruiz-Narvaez, P Kraft, H Campos - The American journal of …, 2007 - Elsevier
Abstract Background: Δ 6-Desaturase (FADS2) is the rate-limiting step in the
polyunsaturated fatty acid (PUFA) biosynthetic pathway. Objective: The aim was to test …

Effect of dietary monosodium glutamate on trans fat-induced nonalcoholic fatty liver disease

KS Collison, Z Maqbool, SM Saleh, A Inglis… - Journal of lipid …, 2009 - ASBMB
The effects of dietary monosodium glutamate (MSG) on trans-fatty acid (TFA)-induced
nonalcoholic fatty liver disease (NAFLD) are addressed in an animal model. We used …

[HTML][HTML] Maternal fatty acids in pregnancy, FADS polymorphisms, and child intelligence quotient at 8 y of age

CD Steer, E Lattka, B Koletzko, J Golding… - The American journal of …, 2013 - Elsevier
Background: Brain tissue is selectively enriched with highly unsaturated fatty acids (FAs).
Altering the maternal FA status in pregnancy may improve fetal neural development with …