Nrf2 as a novel molecular target for chemoprevention

JS Lee, YJ Surh - Cancer letters, 2005 - Elsevier
One of the rational and effective strategies for chemoprevention is the blockade of DNA
damage caused by carcinogenic insult. This can be achieved either by reducing the …

Curcumin and its analogues: potential anticancer agents

DK Agrawal, PK Mishra - Medicinal research reviews, 2010 - Wiley Online Library
This review chronicles the exploration of the curcumin in terms of development of analogues
for the anticancer activity over the last century. Curcumin is a natural phytochemical …

Recent advances in the investigation of curcuminoids

H Itokawa, Q Shi, T Akiyama, SL Morris-Natschke… - Chinese Medicine, 2008 - Springer
Abstract More than 30 Curcuma species (Zingiberaceae) are found in Asia, where the
rhizomes of these plants are used as both food and medicine, such as in traditional Chinese …

Photochemoprevention of skin cancer by botanical agents

S F'guyer, F Afaq, H Mukhtar - Photodermatology …, 2003 - Wiley Online Library
Photochemoprevention has become an important armamentarium in the fight against
ultraviolet radiation (UVR)‐induced damage to the skin. Among many UVR‐induced …

Cyclooxygenases in the skin: pharmacological and toxicological implications

JL Lee, H Mukhtar, DR Bickers, L Kopelovich… - Toxicology and applied …, 2003 - Elsevier
Cyclooxygenase (COX), a prostaglandin-endoperoxide synthase (PTGS), catalyzes the
formation of prostaglandins from arachidonic acid. Prostaglandins are lipid signaling …

[HTML][HTML] Curcumin reverses breast tumor exosomes mediated immune suppression of NK cell tumor cytotoxicity

HG Zhang, H Kim, C Liu, S Yu, J Wang… - … et Biophysica Acta (BBA …, 2007 - Elsevier
An important characteristic of tumors is that they at some point in their development
overcome the surveillance of the immune system. Tumors secrete exosomes, multivesicular …

Ethnopharmacological uses, phytochemistry, biological activities, and therapeutic applications of Alpinia oxyphylla Miquel: A review

Q Zhang, Y Zheng, X Hu, X Hu, W Lv, D Lv… - Journal of …, 2018 - Elsevier
Abstract Ethnopharmacological usages Fructus Alpiniae oxyphyllae (A. oxyphylla) is an
important medicinal plant that is used not only as an edible fruit, but also as an important …

Breaking the relay in deregulated cellular signal transduction as a rationale for chemoprevention with anti-inflammatory phytochemicals

JK Kundu, YJ Surh - … Research/Fundamental and Molecular Mechanisms of …, 2005 - Elsevier
Center to the cancer biology is disrupted intracellular signaling network, which transmits
improper signals resulting in abnormal cellular functioning. Therefore, modulation of …

Anti-proliferative activity of A. Oxyphylla and its bioactive constituent nootkatone in colorectal cancer cells

E Yoo, J Lee, P Lertpatipanpong, J Ryu, CT Kim… - BMC cancer, 2020 - Springer
Background A. oxyphylla extract is known to possess a wide range of pharmacological
activites. However, the molecular mechanism of A. oxyphylla and its bioactive compound …

Anti-inflammatory activity of naturally occuring diarylheptanoids–A review

C Vanucci-Bacqué, F Bedos-Belval - Bioorganic & Medicinal Chemistry, 2021 - Elsevier
Inflammation involving the innate and adaptive immune systems is a normal response to
infection. However, if it becomes uncontrolled, inflammation may result in autoimmune or …