The challenge of HIV treatment in an era of polypharmacy

D Back, C Marzolini - Journal of the International AIDS Society, 2020 - Wiley Online Library
Introduction The availability of potent antiretroviral therapy has transformed HIV infection into
a chronic disease such that people living with HIV (PLWH) have a near normal life …

Aging with HIV

G Guaraldi, J Milic, C Mussini - Current HIV/AIDS Reports, 2019 - Springer
Abstract Purpose of Review This review points out unmet medical needs and open research
questions of older adults living with HIV. Starting from the definition of aging in HIV, it …

[HTML][HTML] Non-communicable disease comorbidities in HIV patients: diabetes, hypertension, heart disease, and obstructive sleep apnea as a neglected issue

F Hadavandsiri, M Shafaati, S Mohammad Nejad… - Scientific Reports, 2023 - nature.com
The present study evaluates the non-communicable disease (NCD) patterns and related risk
factors among people living with HIV (PLWH) in Iran. This national cross-sectional survey …

Non-HIV comorbid conditions and polypharmacy among people living with HIV age 65 or older compared with HIV-negative individuals age 65 or older in the United …

AM Kong, A Pozen, K Anastos, EA Kelvin… - AIDS patient care and …, 2019 - liebertpub.com
The number of people living with HIV (PLWH)≥ 65 years is increasing in the United States.
By 2035, the proportion of PLWH in this age group is projected to be 27%. As PLWH live …

Chronic inflammation mediates brain injury in HIV infection: relevance for cure strategies

JC McArthur, TP Johnson - Current opinion in neurology, 2020 - journals.lww.com
As therapies are developed to cure HIV, it is important to protect the CNS from additional
immune-mediated damage. Adjunctive therapies to restore glial function, reduce …

[HTML][HTML] Statins for primary cardiovascular disease prevention among people with HIV: emergent directions

KV Fitch, ES Fulda, SK Grinspoon - Current Opinion in HIV and …, 2022 - journals.lww.com
Prevention of CVD among the aging population of people with controlled, but chronic, HIV is
vital. Data exploring primary prevention in this context are thus far limited. The Randomized …

[HTML][HTML] Cardiovascular disease and risk assessment in people living with HIV: Current practices and novel perspectives

PC Fragkou, CD Moschopoulos, D Dimopoulou… - Hellenic Journal of …, 2023 - Elsevier
Human immunodeficiency virus (HIV) infection represents a major cardiovascular risk factor,
and the cumulative cardiovascular disease (CVD) burden among aging people living with …

Utilizing electronic health record data to understand comorbidity burden among people living with HIV: a machine learning approach

X Yang, J Zhang, S Chen, S Weissman, B Olatosi, X Li - Aids, 2021 - journals.lww.com
Objectives: An understanding of the predictors of comorbidity among people living with HIV
(PLWH) is critical for effective HIV care management. In this study, we identified predictors of …

Projection of age of individuals living with HIV and time since ART initiation in 2030: estimates for France

L Marty, Y Diawara, A Rachas, S Grabar… - Journal of the …, 2022 - Wiley Online Library
Introduction Thanks to antiretroviral treatment (ART), people living with HIV (PLHIV) are
living longer and ageing. However, ageing involves increased risks of co‐morbidities, which …

[HTML][HTML] Frequency of non-communicable diseases in people 50 years of age and older receiving HIV care in Latin America

PF Belaunzaran-Zamudio, Y Caro-Vega, MJ Giganti… - PLoS …, 2020 - journals.plos.org
Background A growing population of older adults with HIV will increase demands on HIV-
related healthcare. Nearly a quarter of people receiving care for HIV in Latin America are …