Global inequities in precision medicine and molecular cancer research

TM Drake, SR Knight, EM Harrison, K Søreide - Frontiers in Oncology, 2018 - frontiersin.org
Precision medicine based upon molecular testing is heralded as a revolution in how cancer
is prevented, diagnosed, and treated. Large efforts across the world aim to conduct …

Genetic susceptibility in cervical cancer: from bench to bedside

A Bahrami, M Hasanzadeh… - Journal of cellular …, 2018 - Wiley Online Library
Cervical cancer (CC) is the third most common malignancy in women globally, and
persistent infection with the oncogenic human papillomaviruses (HPV) is recognized as the …

Prevalent high-risk HPV infection and vaginal microbiota in Nigerian women

EO Dareng, B Ma, AO Famooto… - Epidemiology & …, 2016 - cambridge.org
In this study, we evaluated the association between high-risk human papillomavirus (hrHPV)
and the vaginal microbiome. Participants were recruited in Nigeria between April and …

Mycoplasma hominis and Mycoplasma genitalium in the Vaginal Microbiota and Persistent High-Risk Human Papillomavirus Infection

SN Adebamowo, B Ma, D Zella, A Famooto… - Frontiers in public …, 2017 - frontiersin.org
Background Recent studies have suggested that the vaginal microenvironment plays a role
in persistence of high-risk human papillomavirus (hrHPV) infection and thus cervical …

Persistent low-risk and high-risk human papillomavirus infections of the uterine cervix in HIV-negative and HIV-positive women

SN Adebamowo, O Olawande, A Famooto… - Frontiers in Public …, 2017 - frontiersin.org
Background The prevalence, persistence, and multiplicity of human papillomavirus (HPV)
infection appears different comparing HIV-positive to HIV-negative women. In this study, we …

Genome, HLA and polygenic risk score analyses for prevalent and persistent cervical human papillomavirus (HPV) infections

SN Adebamowo, A Adeyemo, A Adebayo… - European Journal of …, 2024 - nature.com
Genetic variants that underlie susceptibility to cervical high-risk human papillomavirus
(hrHPV) infections are largely unknown. We conducted discovery genome-wide association …

Genome-wide association study of prevalent and persistent cervical high-risk human papillomavirus (HPV) infection

SN Adebamowo, AA Adeyemo, CN Rotimi… - BMC medical …, 2020 - Springer
Background Genetic factors may influence the susceptibility to high-risk (hr) human
papillomavirus (HPV) infection and persistence. We conducted the first genome-wide …

Cohort profile: African Collaborative Center for Microbiome and Genomics Research's (ACCME's) Human Papillomavirus (HPV) and Cervical Cancer Study

SN Adebamowo, EO Dareng… - International journal …, 2017 - academic.oup.com
Globally, cervical cancer is the fourth most common cancer among women, with an
estimated 528 000 new cases in 2012. 1 Although it remains a significant public health …

Clearance of type-specific, low-risk, and high-risk cervical human papillomavirus infections in HIV-negative and HIV-positive women

SN Adebamowo, A Famooto, EO Dareng… - Journal of global …, 2018 - ascopubs.org
Purpose There is a dearth of data on clearance of cervical human papillomavirus (HPV)
infection among women in West Africa. We examined the clearance of low-risk (lr) and high …

Recent insights into the control of human papillomavirus (HPV) genome stability, loss, and degradation

C Fisher - Journal of clinical medicine, 2015 - mdpi.com
Most human papillomavirus (HPV) antiviral strategies have focused upon inhibiting viral
DNA replication, but it is increasingly apparent that viral DNA levels can be chemically …