[HTML][HTML] Role of Efflux Pumps on Antimicrobial Resistance in Pseudomonas aeruginosa
AB Lorusso, JA Carrara, CDN Barroso, FF Tuon… - International journal of …, 2022 - mdpi.com
Antimicrobial resistance is an old and silent pandemic. Resistant organisms emerge in
parallel with new antibiotics, leading to a major global public health crisis over time …
parallel with new antibiotics, leading to a major global public health crisis over time …
[HTML][HTML] The Art of War with Pseudomonas aeruginosa: Targeting Mex Efflux Pumps Directly to Strategically Enhance Antipseudomonal Drug Efficacy
Pseudomonas aeruginosa (P. aeruginosa) poses a grave clinical challenge due to its
multidrug resistance (MDR) phenotype, leading to severe and life-threatening infections …
multidrug resistance (MDR) phenotype, leading to severe and life-threatening infections …
[HTML][HTML] Emergence of Aeromonas veronii strain co-harboring blaKPC–2, mcr-3.17, and tmexC3.2-tmexD3.3-toprJ1b cluster from hospital sewage in China
Z Zhu, S Wu, J Zhu, T Wang, Y Wen, C Yang… - Frontiers in …, 2023 - frontiersin.org
Introduction The raise of multi-drug resistant bacteria involving carbapenem, colistin, or
tigecycline resistance constitutes a threat to public health, which partly results from the …
tigecycline resistance constitutes a threat to public health, which partly results from the …
Klebsiella Pneumoniae: An Update on Antibiotic Resistance Mechanisms
M Karami-Zarandi, HA Rahdar, H Esmaeili… - Future …, 2023 - Taylor & Francis
Klebsiella pneumoniae colonizes mucosal surfaces of healthy humans and is responsible
for one third of all Gram-negative infections in hospitalized patients. K. pneumoniae is …
for one third of all Gram-negative infections in hospitalized patients. K. pneumoniae is …
Conjugative plasmids facilitate the transmission of tmexCD2-toprJ2 among carbapenem-resistant Klebsiella pneumoniae
H Yao, T Zhang, K Peng, J Peng, X Liu, Z Xia… - Science of the Total …, 2024 - Elsevier
Carbapenem-resistant Klebsiella pneumoniae (CRKP) is a great threat to global public
health. The emergence of tmexCD-toprJ greatly weakened the efficacy of tigecycline in the …
health. The emergence of tmexCD-toprJ greatly weakened the efficacy of tigecycline in the …
[HTML][HTML] Emergence and plasmid cointegration-based evolution of NDM-1-producing ST107 Citrobacter freundii high-risk resistant clone in China
H Liu, Y Tu, J He, Q Xu, X Zhang, X Mu, M Chen… - International Journal of …, 2024 - Elsevier
Carbapenem-resistant Citrobacter freundii (CRCF) poses an enormous challenge in the
health care setting. However, the epidemiology and plasmid dynamic evolution of this …
health care setting. However, the epidemiology and plasmid dynamic evolution of this …
First detection of tet (X4)-positive Enterobacterales in retail vegetables and clonal spread of Escherichia coli ST195 producing Tet (X4) in animals, foods, and humans …
C Yue, X Gao, L Lu, YY Liu, LC Lv, X He, G Gao… - International Journal of …, 2023 - Elsevier
The mobile tigecycline-resistant gene tet (X4), which confers resistance to all tetracyclines,
has been identified in bacterial isolates from various sources. However, there are no reports …
has been identified in bacterial isolates from various sources. However, there are no reports …
[HTML][HTML] Role of efflux pumps, their inhibitors, and regulators in colistin resistance
Y Ding, J Hao, W Xiao, C Ye, X Xiao, C Jian… - Frontiers in …, 2023 - frontiersin.org
Colistin is highly promising against multidrug-resistant and extensively drug-resistant
bacteria clinically. Bacteria are resistant to colistin mainly through mcr and chromosome …
bacteria clinically. Bacteria are resistant to colistin mainly through mcr and chromosome …
[PDF][PDF] Dissemination of the mobilised RND efflux pump gene cluster tmexCD-toprJ among Klebsiella pneumoniae
C Liu, J Guo, M Lu, N Shen, P Du - Lancet Microbe, 2023 - researchgate.net
K pneumoniae has been widely discovered in samples from patients, animals, and food in
China, 2 conferring multidrug resistance, particularly to tigecycline, one of the last-line …
China, 2 conferring multidrug resistance, particularly to tigecycline, one of the last-line …
Pseudomonas Acts as a Reservoir of Novel Tigecycline Resistance Efflux Pump tmexC6D6-toprJ1b and tmexCD-toprJ Variants
CZ Wang, X Gao, XH Liang, LC Lv, LT Lu… - Microbiology …, 2023 - Am Soc Microbiol
Several variants of the plasmid-carried tigecycline resistance gene cluster, tmexCD-toprJ,
have been identified. This study characterized another novel variant, tmexC6D6-toprJ1b …
have been identified. This study characterized another novel variant, tmexC6D6-toprJ1b …