Health beneficial and pharmacological properties of p-cymene
A Balahbib, N El Omari, NEL Hachlafi, F Lakhdar… - Food and Chemical …, 2021 - Elsevier
Abstract p-cymene also known as p-cymol or p-isopropyltoluene is an alkyl-substituted
aromatic compound naturally occurring in essential oils (EOs) of various aromatic plants …
aromatic compound naturally occurring in essential oils (EOs) of various aromatic plants …
[HTML][HTML] Metal-and metalloid-based compounds to target and reverse cancer multidrug resistance
Drug resistance remains the major cause of cancer treatment failure especially at the late
stage of the disease. However, based on their versatile chemistry, metal and metalloid …
stage of the disease. However, based on their versatile chemistry, metal and metalloid …
Design concepts of half-sandwich organoruthenium anticancer agents based on bidentate bioactive ligands
The small molecule anticancer agent cisplatin and its Pt (II) analogs carboplatin and
oxaliplatin are widely used to treat a variety of tumorigenic diseases. Despite their structural …
oxaliplatin are widely used to treat a variety of tumorigenic diseases. Despite their structural …
Non-platinum complexes containing releasable biologically active ligands
P Štarha, Z Trávníček - Coordination Chemistry Reviews, 2019 - Elsevier
Since the discovery of anticancer activity of cisplatin and other transition metal complexes, a
lot of compounds have been reported as containing ligand (s) bearing its (their) own …
lot of compounds have been reported as containing ligand (s) bearing its (their) own …
Structure–activity relationships of 8-hydroxyquinoline-derived Mannich bases with tertiary amines targeting multidrug-resistant cancer
A recently proposed strategy to overcome multidrug resistance (MDR) in cancer is to target
the collateral sensitivity of otherwise resistant cells. We designed a library of 120 …
the collateral sensitivity of otherwise resistant cells. We designed a library of 120 …
Half-Sandwich Iridium(III), Rhodium(III), and Ruthenium(II) Complexes Chelating Hybrid sp2-N/sp3-N Donor Ligands to Achieve Improved Anticancer Selectivity
L Guo, P Li, J Li, Y Gong, X Li, Y Liu, K Yu… - Inorganic …, 2023 - ACS Publications
The biological efficacy of half-sandwich platinum group organometallic complexes of the
formula [(η5-Cpx)/(η6-arene) M (XY) Cl] 0/+(XY= bidentate ligands; Cpx= functionalized …
formula [(η5-Cpx)/(η6-arene) M (XY) Cl] 0/+(XY= bidentate ligands; Cpx= functionalized …
Half-sandwich complexes of platinum group metals (Ir, Rh, Ru and Os) and some recent biological and catalytic applications
JM Gichumbi, HB Friedrich - Journal of Organometallic Chemistry, 2018 - Elsevier
Half-sandwich complexes of the platinum group metals serve as excellent precursors and
find many applications in biological and catalytic applications. This review focuses on the …
find many applications in biological and catalytic applications. This review focuses on the …
RuII(p-cymene) Compounds as Effective and Selective Anticancer Candidates with No Toxicity in Vivo
Ruthenium (II) complexes are currently considered a viable alternative to the widely used
platinum complexes as efficient anticancer agents. We herein present the synthesis and …
platinum complexes as efficient anticancer agents. We herein present the synthesis and …
[HTML][HTML] Binding mechanisms of half-sandwich Rh (III) and Ru (II) arene complexes on human serum albumin: A comparative study
Various half-sandwich ruthenium (II) arene complexes and rhodium (III) arene complexes
have been intensively investigated due to their prominent anticancer activity. The interaction …
have been intensively investigated due to their prominent anticancer activity. The interaction …
[HTML][HTML] Anticancer half-sandwich rhodium (III) complexes
Platinum-based anticancer drugs are most likely the most successful group of bioinorganic
compounds. Their apparent disadvantages have led to the development of anticancer …
compounds. Their apparent disadvantages have led to the development of anticancer …