Key to understanding the neuronal basis of consciousness is the characterization of the
neural signatures of changes in level of consciousness during sleep. Here we analysed …

Background Significant advances have been made in our understanding of subcortical
processes related to anesthetic-and sleep-induced unconsciousness, but the associated …

Maintained gamma band activity is a key element of higher brain function, participating in
perception, executive function, and memory. The pedunculopontine nucleus (PPN), as part …

Alpha-synuclein induced degeneration of the midbrain substantia nigra pars compact (SNc)
dopaminergic neurons causes Parkinson's disease (PD). Rodent studies demonstrate that …

Background Angelman syndrome (AS) is a neurodevelopmental disorder characterized by
intellectual disability, speech and motor impairments, epilepsy, abnormal sleep, and …

Recent studies have shown that slow cortical potentials in archi‐, paleo‐and neocortex can
phase‐lock with nasal respiration. In some of these areas, gamma activity (γ: 30–100 Hz) is …

Urethane is a general anaesthetic widely used in animal research. The state of urethane
anaesthesia is unique because it alternates between macroscopically distinct electrographic …

Ibogaine is a psychedelic alkaloid that has attracted large scientific interest because of its
antiaddictive properties in observational studies in humans as well as in animal models. Its …

The sleep-wake cycle is constituted by three behavioral states: wakefulness (W), non-REM
(NREM) and REM sleep. These states are associated with drastic changes in cognitive …

Ibogaine is a potent psychedelic alkaloid that has been the focus of intense research
because of its intriguing anti-addictive properties. According to anecdotic reports, ibogaine …