This article presents the revised consensus criteria for the diagnosis of frontotemporal
dysfunction in amyotrophic lateral sclerosis (ALS) based on an international research …

Early reports of cognitive and behavioural deficits in motor neuron disease might have been
overlooked initially, but the concept of a frontotemporal dementia-motor neuron disease …

Functional and structural connectivity measures, as assessed by means of functional and
diffusion MRI, are emerging as potential intermediate biomarkers for Alzheimer disease (AD) …

C9orf72 hexanucleotide repeat expansions are the most common cause of familial
frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS) worldwide. The …

In the past two decades, structural and functional neuroimaging findings have greatly
modified longstanding notions regarding the pathophysiology of amyotrophic lateral …

Objective The purpose of this study was to identify subtypes of amyotrophic lateral sclerosis
(ALS) by comparing patterns of neurodegeneration using brain magnetic resonance …

Amyotrophic lateral sclerosis is a devastating disease characterized primarily by motor
system degeneration, with clinical evidence of cognitive and behavioural change in up to …

Diffusion tensor imaging can identify amyotrophic lateral sclerosis-associated patterns of
brain alterations at the group level. Recently, a neuropathological staging system for …

Hexanucleotide repeat expansions in C9ORF72 are the most common known genetic cause
of familial and sporadic frontotemporal dementia and amyotrophic lateral sclerosis. Previous …

Objective: We investigated a large sample of patients with amyotrophic lateral sclerosis
(ALS) at rest in order to assess the value of 18F-2-fluoro-2-deoxy-d-glucose (18F-FDG) PET …