Obesity is a major public health problem that continues to be one of the leading risk factors
for premature death. Early life is a critical period of time when the gut microbiota and host …

Evidence suggests that bariatric surgery alters gut microbiota, although its impact at
compositional and functional level is not well described. In this review, the most relevant …

The gut microbiota is important in the occurrence and development of obesity. It can not only
via its metabolites, but also through microbiota-gut-brain-liver interactions, directly or …

Bile acids are acknowledged as signaling molecules involved in metabolic syndrome. The
Takeda G protein-coupled receptor 5 (TGR5) functions as a significant bile acid receptor …

Although bile acids play a notable role in depression, the pathological significance of the
bile acid TGR5 membrane-type receptor in this disorder remains elusive. Using depression …

In the present study, juvenile hybrid grouper (Epinephelus fuscoguttatus♀× E.
lanceolatus♂) were intraperitoneally injected with taurocholic acid (I-TCA), obeticholic acid …

The regulation of bile acid pathways has become a particularly promising therapeutic
strategy for a variety of metabolic disorders, cancers, and diseases. However, the …

Cordyceps sinensis (CS) has been widely used as a dietary supplement or traditional
medicine for the prevention, treatment, and prognostication of various diseases, because of …

Bile acids (BAs) are pleiotropic regulators of metabolism. Elevated levels of hepatic and
circulating BAs improve energy metabolism in peripheral organs, but the precise …

In recent years, there has been increasing interest in studying gut microbiome-derived
hydrolases in relation to oral drug metabolism, particularly focusing on natural product …