Single-cell microfluidic impedance cytometry: From raw signals to cell phenotypes using data analytics

C Honrado, P Bisegna, NS Swami, F Caselli - Lab on a Chip, 2021 - pubs.rsc.org
The biophysical analysis of single-cells by microfluidic impedance cytometry is emerging as
a label-free and high-throughput means to stratify the heterogeneity of cellular systems …

Cell cytometry: Review and perspective on biotechnological advances

A Vembadi, A Menachery… - Frontiers in bioengineering …, 2019 - frontiersin.org
Cell identification and enumeration are essential procedures within clinical and research
laboratories. For over 150 years, quantitative investigation of body fluids such as counts of …

Positional dependence of particles and cells in microfluidic electrical impedance flow cytometry: Origin, challenges and opportunities

H Daguerre, M Solsona, J Cottet, M Gauthier… - Lab on a Chip, 2020 - pubs.rsc.org
Microfluidic electrical impedance flow cytometry is now a well-known and established
method for single-cell analysis. Given the richness of the information provided by impedance …

Review and perspectives on microfluidic flow cytometers

RJ Yang, LM Fu, HH Hou - Sensors and Actuators B: Chemical, 2018 - Elsevier
Modern microflow cytometers are sophisticated instruments capable of measuring multiple
physical characteristics of a single cell simultaneously as the cells flow in suspension …

Microfluidic-Based Oxygen (O2) Sensors for On-Chip Monitoring of Cell, Tissue and Organ Metabolism

M Azimzadeh, P Khashayar, M Amereh, N Tasnim… - Biosensors, 2021 - mdpi.com
Oxygen (O2) quantification is essential for assessing cell metabolism, and its consumption in
cell culture is an important indicator of cell viability. Recent advances in microfluidics have …

Floating-electrode-enabled impedance cytometry for single-cell 3D localization

Q Fang, Y Feng, J Zhu, L Huang, W Wang - Analytical Chemistry, 2023 - ACS Publications
As a label-free, low-cost, and noninvasive tool, impedance measurement has been widely
used in single-cell characterization analysis. However, due to the tiny volume of cells, the …

High-throughput label-free characterization of viable, necrotic and apoptotic human lymphoma cells in a coplanar-electrode microfluidic impedance chip

A De Ninno, R Reale, A Giovinazzo, FR Bertani… - Biosensors and …, 2020 - Elsevier
The study and the characterization of cell death mechanisms are fundamental in cell biology
research. Traditional death/viability assays usually involve laborious sample preparation …

Enzyme-free catalytic hairpin assembly reaction-mediated micro-orifice resistance assay for the ultrasensitive and low-cost detection of Listeria monocytogenes

L Ren, F Hong, Y Chen - Biosensors and Bioelectronics, 2022 - Elsevier
The rapid, reliable, ultra-sensitive, and cost-saving detection of Listeria monocytogenes (L.
monocytogenes) has substantial implications for food safety. Thus, we developed a novel …

Machine learning-based impedance system for real-time recognition of antibiotic-susceptible bacteria with parallel cytometry

T Tang, X Liu, Y Yuan, R Kiya, T Zhang, Y Yang… - Sensors and Actuators B …, 2023 - Elsevier
Impedance cytometry has enabled label-free and fast antibiotic susceptibility testing of
bacterial single cells. Here, a machine learning-based impedance system is provided to …

Accurate profiling of blood components in microliter with position-insensitive coplanar electrodes-based cytometry

J Zhong, Q Tang, M Liang, Y Ai - Sensors and Actuators B: Chemical, 2022 - Elsevier
Differentiating and counting blood cell subtypes are essential for medical diagnosis.
Microfluidic impedance-based cytometry has been discussed in the past decade as cost …