Knee osteoarthritis: a review of pathogenesis and state-of-the-art non-operative therapeutic considerations

D Primorac, V Molnar, E Rod, Ž Jeleč, F Čukelj… - Genes, 2020 - mdpi.com
Being the most common musculoskeletal progressive condition, osteoarthritis is an
interesting target for research. It is estimated that the prevalence of knee osteoarthritis (OA) …

The role of inflammation in the pathogenesis of osteoarthritis

YY Chow, KY Chin - Mediators of inflammation, 2020 - Wiley Online Library
A joint is the point of connection between two bones in our body. Inflammation of the joint
leads to several diseases, including osteoarthritis, which is the concern of this review …

Cartilage tissue engineering: From proinflammatory and anti‑inflammatory cytokines to osteoarthritis treatments

S Liu, Z Deng, K Chen, S Jian… - Molecular …, 2022 - spandidos-publications.com
Osteoarthritis (OA), one of the most common joint diseases, is characterized by fibrosis,
rhagadia, ulcers and attrition of articular cartilage due to a number of factors. The etiology of …

Gender-specific differential expression of exosomal miRNA in synovial fluid of patients with osteoarthritis

R Kolhe, M Hunter, S Liu, RN Jadeja, C Pundkar… - Scientific reports, 2017 - nature.com
The pathogenesis of osteoarthritis (OA) is poorly understood, and therapeutic approaches
are limited to preventing progression of the disease. Recent studies have shown that …

[HTML][HTML] Osteoarthritis Year in Review 2016: biomarkers (biochemical markers)

A Mobasheri, AC Bay-Jensen, WE Van Spil… - Osteoarthritis and …, 2017 - Elsevier
Purpose The aim of this “Year in Review” article is to summarize and discuss the
implications of biochemical marker related articles published between the Osteoarthritis …

Faecal microbiota transplantation from metabolically compromised human donors accelerates osteoarthritis in mice

ZY Huang, J Chen, BL Li, B Zeng, CH Chou… - Annals of the …, 2020 - ard.bmj.com
Objectives Emerging evidence suggests that the microbiome plays an important role in the
pathogenesis of osteoarthritis (OA). We aimed to test the two-hit model of OA pathogenesis …

Review of prospects of biological fluid biomarkers in osteoarthritis

LT Nguyen, AR Sharma, C Chakraborty… - International journal of …, 2017 - mdpi.com
Osteoarthritis (OA) is a degenerative disease of the joints and is one of the leading causes of
disability in adults. However, there are no key therapeutics for OA and medical treatment is …

[HTML][HTML] Osteoarthritis biomarkers: year in review

FE Watt - Osteoarthritis and cartilage, 2018 - Elsevier
Objective To summarise important findings from biomarker studies relevant to osteoarthritis
(OA), published between April 2016 and March 2017; to consider these findings in the …

Secreted factors and EV-miRNAs orchestrate the healing capacity of adipose mesenchymal stem cells for the treatment of knee osteoarthritis

E Ragni, C Perucca Orfei, P De Luca… - International journal of …, 2020 - mdpi.com
Mesenchymal stem cells (MSCs) derived from adipose tissue and used either as expanded
cells or minimally manipulated cell preparations showed positive clinical outcomes in …

Effects of externally-applied, non-pharmacological Interventions on short-and long-term symptoms and inflammatory cytokine levels in patients with knee osteoarthritis …

Z Wang, H Xu, Z Wang, H Zhou, J Diao… - Frontiers in …, 2023 - frontiersin.org
Background With the continuous development of clinical medicine, an increasing number of
non-pharmacological interventions have been applied for the treatment of knee …