Hepatocellular carcinoma surveillance—Utilization, barriers and the impact of changing aetiology

DQ Huang, AG Singal, F Kanwal… - Nature Reviews …, 2023 - nature.com
Hepatocellular carcinoma (HCC) is the third leading cause of cancer death worldwide.
Surveillance for HCC is critical for early detection and treatment, but fewer than one-quarter …

[HTML][HTML] Carbohydrate-based drugs launched during 2000− 2021

X Cao, X Du, H Jiao, Q An, R Chen, P Fang… - … Pharmaceutica Sinica B, 2022 - Elsevier
Carbohydrates are fundamental molecules involved in nearly all aspects of lives, such as
being involved in formating the genetic and energy materials, supporting the structure of …

Cancer vaccines: toward the next breakthrough in cancer immunotherapy

Y Igarashi, T Sasada - Journal of immunology research, 2020 - Wiley Online Library
Until now, three types of well‐recognized cancer treatments have been developed, ie,
surgery, chemotherapy, and radiotherapy; these either remove or directly attack the cancer …

Medicinal chemistry strategies for discovering antivirals effective against drug-resistant viruses

Y Ma, E Frutos-Beltrán, D Kang… - Chemical Society …, 2021 - pubs.rsc.org
During the last forty years we have witnessed impressive advances in the field of antiviral
drug discovery culminating with the introduction of therapies able to stop human …

MAFLD: Renovation of clinical practice and disease awareness of fatty liver

T Kawaguchi, T Tsutsumi, D Nakano… - Hepatology …, 2022 - Wiley Online Library
Recently, international expert panels have proposed a new definition of fatty liver: metabolic
dysfunction‐associated fatty liver disease (MAFLD). MAFLD is not just a simple renaming of …

[HTML][HTML] Viral hepatitis update: Progress and perspectives

MB Pisano, CG Giadans, DM Flichman… - World journal of …, 2021 - ncbi.nlm.nih.gov
Viral hepatitis, secondary to infection with hepatitis A, B, C, D, and E viruses, are a major
public health problem and an important cause of morbidity and mortality. Despite the huge …

Hepatocellular carcinoma: a narrative review on current knowledge and future prospects

B Alawyia, C Constantinou - Current Treatment Options in Oncology, 2023 - Springer
Opinion statement Hepatocellular carcinoma is the fourth leading cause of cancer-related
deaths worldwide and its associated mortality rate is expected to rise within the next decade …

Natural history and hepatocellular carcinoma risk in untreated chronic hepatitis B patients with indeterminate phase

DQ Huang, X Li, MH Le, AK Le, YH Yeo… - Clinical …, 2022 - Elsevier
Background & Aims Many patients with chronic hepatitis B (CHB) may not conform to any of
the defined phases and hence are classified as indeterminate. We aimed to characterize the …

An interpretable machine learning approach for hepatitis b diagnosis

G Obaido, B Ogbuokiri, TG Swart, N Ayawei… - Applied sciences, 2022 - mdpi.com
Hepatitis B is a potentially deadly liver infection caused by the hepatitis B virus. It is a serious
public health problem globally. Substantial efforts have been made to apply machine …

Interferon and interferon-stimulated genes in HBV treatment

Q Li, B Sun, Y Zhuo, Z Jiang, R Li, C Lin, Y Jin… - Frontiers in …, 2022 - frontiersin.org
Human hepatitis B virus (HBV) is a small enveloped DNA virus with a complex life cycle. It is
the causative agent of acute and chronic hepatitis. HBV can resist immune system …