Tumor microenvironment remodeling in oral cancer: Application of plant derived-natural products and nanomaterials
Oral cancers consist of squamous cell carcinoma (SCC) and other malignancies in the
mouth with varying degrees of invasion and differentiation. For many years, different …
mouth with varying degrees of invasion and differentiation. For many years, different …
Veliparib (ABT-888), a PARP inhibitor potentiates the cytotoxic activity of 5-fluorouracil by inhibiting MMR pathway through deregulation of MSH6 in colorectal cancer …
Objective Sensitization of mismatch repair (MMR)-deficient colorectal cancer (CRC) cells by
5-Fluorouracil (5-FU) is well-documented. But not much is known about the treatment of …
5-Fluorouracil (5-FU) is well-documented. But not much is known about the treatment of …
Combination therapy as a promising way to fight oral cancer
Oral cancer is a highly aggressive tumor with invasive properties that can lead to metastasis
and high mortality rates. Conventional treatment strategies, such as surgery, chemotherapy …
and high mortality rates. Conventional treatment strategies, such as surgery, chemotherapy …
Olaparib enhances the Resveratrol-mediated apoptosis in breast cancer cells by inhibiting the homologous recombination repair pathway
Although sensitization of BRCA-mutated, homologous recombination (HR)-deficient breast
cancer cells through PARP inhibitor is widely studied, not much is known about the …
cancer cells through PARP inhibitor is widely studied, not much is known about the …
[HTML][HTML] Nanostructures for site-specific delivery of oxaliplatin cancer therapy: Versatile nanoplatforms in synergistic cancer therapy
M Bagheri, MA Zandieh, M Daryab, SS Samaei… - Translational …, 2024 - Elsevier
As a clinically approved treatment strategy, chemotherapy-mediated tumor suppression has
been compromised, and in spite of introducing various kinds of anticancer drugs, cancer …
been compromised, and in spite of introducing various kinds of anticancer drugs, cancer …
Combination of Resveratrol and PARP inhibitor Olaparib efficiently deregulates homologous recombination repair pathway in breast cancer cells through inhibition of …
Recently, we reported that a combination of a natural, bioactive compound Resveratrol
(RES) and a PARP inhibitor Olaparib (OLA) deregulated the homologous recombination …
(RES) and a PARP inhibitor Olaparib (OLA) deregulated the homologous recombination …
Curcumin Alone and Combined With PI3K Inhibitors Elicits Positive Effects on Oropharyngeal Cancer Cell Lines Regardless of HPV Status
M Lukoceviciute, M Zupancic… - Anticancer …, 2024 - ar.iiarjournals.org
Background/Aim: Human papillomavirus positive (HPV+) oropharyngeal squamous cell
carcinoma (OPSCC) is rising in incidence. Compared to HPV-negative (HPV–) OPSCC …
carcinoma (OPSCC) is rising in incidence. Compared to HPV-negative (HPV–) OPSCC …
Near infrared-responsive quinacrine–gold hybrid nanoparticles deregulate HSP-70/P300-mediated H3K14 acetylation in ER/PR+ breast cancer stem cells
Aim: This study aimed to determine if quinacrine–gold hybrid nanoparticles (QAuNPs)+ near-
infrared (NIR) deregulate HSP-70/P300 complex-mediated H3K14 acetylation in estrogen …
infrared (NIR) deregulate HSP-70/P300 complex-mediated H3K14 acetylation in estrogen …
Quinacrine inhibits cMET-mediated metastasis and angiogenesis in breast cancer stem cells
A trans-membrane receptor tyrosine kinase, cMET, belonging to the MET proto-oncogene
family, is responsible for cancer metastasis and angiogenesis. But not much is known about …
family, is responsible for cancer metastasis and angiogenesis. But not much is known about …
Scutellarin: pharmacological effects and therapeutic mechanisms in chronic diseases
S Nie, S Zhang, R Wu, Y Zhao, Y Wang… - Frontiers in …, 2024 - frontiersin.org
Scutellarin (SCU), a flavonoid glucuronide derived from Scutellaria barbata and Erigeron
breviscapus, exhibits broad pharmacological effects with promising therapeutic potential in …
breviscapus, exhibits broad pharmacological effects with promising therapeutic potential in …