Analogies with inert soft condensed matter—such as viscoelastic liquids, pastes, foams,
emulsions, colloids, and polymers—can be used to investigate the mechanical response of …

Highly pathogenic bacteria, including Yersinia, Salmonella, E. coli and Clostridia, produce
an amazing array of virulence factors that target Rho proteins. These pathogens exploit …

Embryo implantation into the uterus marks a key transition in mammalian development. In
mice, implantation is mediated by the trophoblast and is accompanied by a morphological …

Cellular architectures are promising in a variety of engineering applications due to attractive
material properties. Additive manufacturing has reduced the difficulty in the fabrication of …

The accumulation and transmission of mechanical stresses in the cell cortex and membrane
determines the mechanics of cell shape and coordinates essential physical behaviors, from …

Cancer cell migration through narrow constrictions generates compressive stresses on the
nucleus that deform it and cause rupture of nuclear membranes. Nuclear membrane rupture …

Cortical formins, pivotal for the assembly of linear actin filaments beneath the membrane,
exert only minor effects on unconfined cell migration of weakly and moderately adherent …

Cellular nuclei are bound by two uniformly separated lipid membranes that are fused with
each other at numerous donut-shaped pores. These membranes are structurally supported …

The bulk of aqueous humor passing through the conventional outflow pathway must cross
the inner wall endothelium of Schlemm's canal (SC), likely through micron-sized …

Transendothelial cell macroaperture (TEM) tunnels control endothelium barrier function and
are triggered by several toxins from pathogenic bacteria that provoke vascular leakage …