Critically ill pediatric patients often require complex medical procedures as well as invasive
testing and monitoring which tend to be painful and anxiety-provoking, necessitating the …

Critically ill children with acute neurologic dysfunction are at risk for a variety of
complications that can be detected by noninvasive bedside neuromonitoring. Continuous …

In the last decades, the advancement of knowledge in analgesia and sedation for critically ill
pediatric patients has been conspicuous and relevant. Many recommendations have …

Infants and children born with CHD are at significant risk for neurodevelopmental delays and
abnormalities. Individualised developmental care is widely recognised as best practice to …

Objectives: To validate the conceptual framework of “criticality,” a new pediatric inpatient
severity measure based on physiology, therapy, and therapeutic intensity calibrated to care …

Importance Adoption of multimodal pain regimens that incorporate nonopioid analgesic
medications to reduce inpatient opioid administration can prevent serious opioid-related …

OBJECTIVES: Assess a machine learning method of serially updated mortality risk. DESIGN:
Retrospective analysis of a national database (Health Facts; Cerner Corporation, Kansas …

OBJECTIVES: To compare the relative associations of lactate, albumin, and the lactate-
albumin ratio (LAR) measured early in disease course against mortality and prevalence of …

Objectives: To assess severity of illness trajectories described by the Criticality Index for
survivors and deaths in five patient groups defined by the sequence of patient care in ICU …

Objective: To examine medication administration records through electronic health record
data to provide a broad description of the pharmaceutical exposure of critically ill children …