Asthma is a heterogenous disease characterized by multiple phenotypes driven by different
mechanisms. The implementation of precision medicine in the management of asthma …

The potential of precision medicine in allergy and asthma has only started to be explored. A
significant clarification in the pathophysiology of rhinitis, chronic rhinosinusitis, asthma, food …

Background Prevalence and severity of allergic diseases have increased worldwide. To
date, respiratory allergy phenotypes are not fully characterized and, along with inflammation …

Lipid mediators play an essential role in the pathogenesis of asthma. Many studies on the
differential expression of sphingolipids and fatty acid exist, but relatively few concerned …

There is increasing evidence that the metabolic status of T cells and macrophages is
associated with severe phenotypes of chronic inflammation, including allergic inflammation …

Background Asthma is a complex, multifactorial disease often linked with sensitization to
house dust mites (HDM). There is a subset of patients that does not respond to available …

Proline and its synthesis enzyme pyrroline-5-carboxylate reductase 1 (PYCR1) are
implicated in epithelial-mesenchymal transition (EMT), yet how proline and PYCR1 function …

Abstract The European Academy of Allergy and Clinical Immunology (EAACI) organized the
first European Strategic Forum on Allergic Diseases and Asthma. The main aim was to bring …

Background Neutrophils consume a large amount of energy when performing their
functions. Compared with other white blood cells, neutrophils contain few mitochondria and …

Background and Objective. Asthma as a chronic heterogeneous disease seriously affects
the quality of life. Incorrect identification for its clinical phenotypes lead to a huge waste of …