How can we better identify early HIV infections?

NE Rosenberg, CD Pilcher, MP Busch… - Current Opinion in HIV …, 2015 - journals.lww.com
There are important recent advances in detection of EHIs at the individual and population
levels. Applying optimal combinations of tests in diagnostic and HIV incidence algorithms is …

[HTML][HTML] Use of HIV recency assays for HIV incidence estimation and other surveillance use cases: systematic review

SN Facente, E Grebe, AD Maher, D Fox… - JMIR public health …, 2022 - publichealth.jmir.org
Background: HIV assays designed to detect recent infection, also known as “recency
assays,” are often used to estimate HIV incidence in a specific country, region, or …

[HTML][HTML] Effect of community-based voluntary counselling and testing on HIV incidence and social and behavioural outcomes (NIMH Project Accept; HPTN 043): a …

TJ Coates, M Kulich, DD Celentano… - The lancet global …, 2014 - thelancet.com
Background Although several interventions have shown reduced HIV incidence in clinical
trials, the community-level effect of effective interventions on the epidemic when scaled up is …

Community viral load, antiretroviral therapy coverage, and HIV incidence in India: a cross-sectional, comparative study

SS Solomon, SH Mehta, AM McFall, AK Srikrishnan… - The lancet HIV, 2016 - thelancet.com
Background HIV incidence is the best measure of treatment-programme effectiveness, but its
measurement is difficult and expensive. The concept of community viral load as a modifiable …

High HIV prevalence and incidence among MSM across 12 cities in India

SS Solomon, SH Mehta, AK Srikrishnan… - Aids, 2015 - journals.lww.com
Objective: To characterize prevalence, incidence, and associated correlates of HIV infection
among MSM in 12 cities across India. Design: Cross-sectional sample using respondent …

Temporal change in population-level prevalence of detectable HIV viraemia and its association with HIV incidence in key populations in India: a serial cross-sectional …

EU Patel, SS Solomon, GM Lucas, AM McFall… - The lancet HIV, 2021 - thelancet.com
Background Population-level prevalence of detectable HIV viraemia (PDV) has been
proposed as a metric for monitoring the population-level effectiveness of HIV treatment as …

Estimating time of HIV-1 infection from next-generation sequence diversity

V Puller, R Neher, J Albert - PLoS Computational Biology, 2017 - journals.plos.org
Estimating the time since infection (TI) in newly diagnosed HIV-1 patients is challenging, but
important to understand the epidemiology of the infection. Here we explore the utility of virus …

High HIV burden among people who inject drugs in 15 Indian cities

GM Lucas, SS Solomon, AK Srikrishnan, A Agrawal… - Aids, 2015 - journals.lww.com
Background: Injecting drug use has historically been the principal driver of the HIV epidemic
in the northeast states of India. However, recent data indicate growing numbers of people …

Facilitating next‐generation pre‐exposure prophylaxis clinical trials using HIV recent infection assays: a consensus statement from the Forum HIV Prevention Trial …

N Parkin, F Gao, E Grebe, A Cutrell… - Clinical …, 2023 - Wiley Online Library
Standard‐of‐care HIV pre‐exposure prophylaxis (PrEP) is highly efficacious, but uptake of
and persistence on a daily oral pill is low in many settings. Evaluation of alternate PrEP …

Young people who inject drugs in India have high HIV incidence and behavioural risk: a cross‐sectional study

L Ganapathi, AM McFall, AK Srikrishnan… - Journal of the …, 2019 - Wiley Online Library
Introduction There are limited data on young people who inject drugs (PWID) from low‐and
middle‐income countries where injection drug use remains a key driver of new HIV …