In the last 20 years, an increasing number of studies have been reported on membrane
active peptides. These peptides exert their biological activity by interacting with the cell …

Synthetic cells are engineered vesicles that can mimic one or more salient features of life.
These features include directed localization, sense‐and‐respond behavior, gene …

Melittin is a prototype of the ubiquitous antimicrobial peptides that induce pores in
membranes. It is commonly used as a molecular device for membrane permeabilization …

Regulated exocytosis and endocytosis are critical to the function of many intercellular
networks, particularly the complex neural circuits underlying mammalian behavior. Kiss-and …

Antimicrobial peptides (AMPs), as a key component of the immune defense systems of
organisms, are a promising solution to the serious threat of drug-resistant bacteria to public …

Highlights•Nanopores are making a strong impact in both basic science and
biotechnology.•Protein nanopores can be engineered with precision and are preferred for …

Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa stand out in
veterinary and human medicine for their role in opportunistic infections and their pathogenic …

The cellular response to subtle membrane damage following exposure to nanosecond
pulsed electric fields (nsPEF) is not well understood. Recent work has shown that when cells …

To intoxicate cells, pore-forming bacterial toxins are evolved to allow for the transmembrane
traffic of different substrates, ranging from small inorganic ions to cell-specific polypeptides …

Due to intrinsic and acquired chemo/radiotherapy-resistance, renal cell carcinoma shows
limited therapeutic response to clinically utilized targeting drugs. Here a tumor-activated …