Pinocembrin: a novel natural compound with versatile pharmacological and biological activities

A Rasul, FM Millimouno, W Ali Eltayb… - BioMed research …, 2013 - Wiley Online Library
Pinocembrin (5, 7‐dihydroxyflavanone) is one of the primary flavonoids isolated from the
variety of plants, mainly from Pinus heartwood, Eucalyptus, Populus, Euphorbia, and …

Site-specific anticancer effects of dietary flavonoid quercetin

K Sak - Nutrition and cancer, 2014 - Taylor & Francis
Food-derived flavonoid quercetin, widely distributed in onions, apples, and tea, is able to
inhibit growth of various cancer cells indicating that this compound can be considered as a …

Nanoemulsion formulation of fisetin improves bioavailability and antitumour activity in mice

H Ragelle, S Crauste-Manciet, J Seguin… - International journal of …, 2012 - Elsevier
The natural flavonoid fisetin (3, 3′, 4′, 7-tetrahydroxyflavone) has shown antitumour
activity but its administration is complicated by its low water solubility. Our aim was to …

Skin cancer, including related pathways and therapy and the role of luteolin derivatives as potential therapeutics

AM Juszczak, U Wöelfle, MZ Končić… - Medicinal research …, 2022 - Wiley Online Library
Cutaneous malignant melanoma is the fastest growing and the most aggressive form of skin
cancer that is diagnosed. However, its incidence is relatively scarce compared to the highest …

Dietary flavonoid fisetin: a novel dual inhibitor of PI3K/Akt and mTOR for prostate cancer management

VM Adhami, DN Syed, N Khan, H Mukhtar - Biochemical pharmacology, 2012 - Elsevier
Epidemiologic and case control population based studies over the past few decades have
identified diet as an important determinant of cancer risk. This evidence has kindled interest …

Liposomal encapsulation of the natural flavonoid fisetin improves bioavailability and antitumor efficacy

J Seguin, L Brullé, R Boyer, YM Lu, MR Romano… - International journal of …, 2013 - Elsevier
The natural flavonoid fisetin (3, 3′, 4′, 7-tetrahydroxyflavone) has shown antiangiogenic
and anticancer properties. Because of fisetin limited water solubility, we designed a …

Recent advances in the biosynthesis, structure–activity relationships, formulations, pharmacology, and clinical trials of fisetin

R Zhong, MA Farag, M Chen, C He, J Xiao - EFood, 2022 - Wiley Online Library
Fisetin is one of the most popular flavonoids found in vegetables and fruits with several
health benefits such as antidiabetic, anticancer, and anti‐inflammatory activities …

[HTML][HTML] Emerging novel drug delivery strategies for bioactive flavonol fisetin in biomedicine

P Mehta, A Pawar, K Mahadik, C Bothiraja - Biomedicine & …, 2018 - Elsevier
Fisetin (FIS), a bioactive flavonol found in the smoke tree (Cotinus coggygria), vegetables,
fruits and nuts. It exhibits various therapeutic activities such as anti-oxidant, anti …

Inhibition of Akt/mTOR signaling by the dietary flavonoid fisetin

DN Syed, VM Adhami, M Imran Khan… - Anti-Cancer Agents in …, 2013 - ingentaconnect.com
Plants have long been providing mankind with remedies of different ailments. Flavonoids, a
family of naturally occurring polyphenolic compounds are ubiquitous in plants. Development …

Designing fisetin nanocrystals for enhanced in cellulo anti-angiogenic and anticancer efficacy

P Ma, J Seguin, NK Ly, LC Henríquez… - International Journal of …, 2022 - Elsevier
We report the formulation, characterization, colloidal stability, and in vitro efficiency of Fisetin
nanocrystals stabilized by poloxamer P407. Such nanocrystals present a nanometer scale …