Two types of cannabinoid receptor have been discovered so far, CB1 (2.1: CBD: 1: CB1:),
cloned in 1990, and CB2 (2.1: CBD: 2: CB2:), cloned in 1993. Distinction between these …

Cannabis (marijuana) is not only a frequently abused drug but also has the potential for the
development of useful agents for the treatment of emesis, anorexia and multiple sclerosis. In …

There are at least two types of cannabinoid receptor, CB1 and CB2, both G protein coupled.
CB1 receptors are expressed predominantly at nerve terminals and mediate inhibition of …

The CB 1 cannabinoid receptor is widely distributed in the central and peripheral nervous
system. Within the neuron, the CB 1 receptor is often localised in axon terminals, and its …

Abstract p] Cannabinoids and their synthetic and endogenous analogs affect a broad range
of physiological functions, including lcardiovascular variables, the most important …

In the first 20 years that followed the purinergic signalling hypothesis in 1972, most scientists
were sceptical about its validity, largely because ATP was so well established as an …

Cardiac contractility in cirrhosis is normal at baseline but hyporesponsive to stimuli, a
phenomenon known as 'cirrhotic cardiomyopathy'. The pathogenesis remains unclear …

During the last decade, research on the molecular biology and genetics of cannabinoid
receptors has led to a remarkable progress in understanding of the endogenous …

The roles of the two cannabinoid receptor subtypes, CB-1 and CB-2, have not been clarified
in cannabinoid-mediated analgesia. We investigated the efficacy of the non-selective …

Staphylococcal pathogenesis is regulated by a two-component quorum-sensing system, agr,
activated by a self-coded autoinducing peptide (AIP). The agr system is widely divergent and …