Immunohistochemistry in gynecologic carcinomas: Practical update with diagnostic and clinical considerations based on the 2020 WHO classification of tumors
N Buza - Seminars in Diagnostic Pathology, 2022 - Elsevier
This review provides an update on immunohistochemistry applications–diagnostic,
prognostic, and predictive–in the pathology evaluation of gynecologic carcinomas. The 5th …
prognostic, and predictive–in the pathology evaluation of gynecologic carcinomas. The 5th …
Interpretation of p16, p53 and mismatch repair protein immunohistochemistry in gynaecological neoplasia
RWC Wong, A Palicelli, L Hoang, N Singh - Diagnostic Histopathology, 2020 - Elsevier
Current management of gynaecological neoplasms is underpinned by their molecular
characteristics. For many neoplasms the underlying genetic abnormalities can be reliably …
characteristics. For many neoplasms the underlying genetic abnormalities can be reliably …
Classification of vulvar squamous cell carcinoma and precursor lesions by p16 and p53 immunohistochemistry: considerations, caveats, and an algorithmic approach
H Yang, N Almadani, EF Thompson, B Tessier-Cloutier… - Modern Pathology, 2023 - Elsevier
There is emerging evidence that vulvar squamous cell carcinoma (VSCC) can be
prognostically subclassified into 3 groups based on human papillomavirus (HPV) and p53 …
prognostically subclassified into 3 groups based on human papillomavirus (HPV) and p53 …
p53 immunohistochemical patterns in HPV-independent squamous cell carcinomas of the vulva and the associated skin lesions: a study of 779 cases
N Rakislova, L Alemany, O Clavero, A Saco… - International Journal of …, 2020 - mdpi.com
Human papillomavirus (HPV)-independent vulvar squamous cell carcinomas (VSCC) and its
precursors frequently harbour TP53 mutations. Recently, six p53 immunohistochemical …
precursors frequently harbour TP53 mutations. Recently, six p53 immunohistochemical …
Oropharyngeal squamous cell carcinoma: p16/p53 immunohistochemistry as a strong predictor of HPV tumour status
N Benzerdjeb, J Tantot, C Blanchet, P Philouze… - …, 2021 - Wiley Online Library
Aims Oropharyngeal squamous cell carcinomas (OPSCC) related to human papillomavirus
(HPV) infection have a better prognosis than those without HPV infection. Although …
(HPV) infection have a better prognosis than those without HPV infection. Although …
High‐grade vulvar intraepithelial neoplasia: comprehensive characterization and long‐term vulvar carcinoma risk
NB Thuijs, M van Beurden, S Duin… - …, 2024 - Wiley Online Library
Aims Adequate diagnosis of human papillomavirus (HPV)‐associated high‐grade
squamous intraepithelial lesion (HSIL) and HPV‐independent vulvar intraepithelial …
squamous intraepithelial lesion (HSIL) and HPV‐independent vulvar intraepithelial …
Abnormal p53 immunohistochemical patterns shed light on the aggressiveness of oral epithelial dysplasia
R Novack, L Zhang, LN Hoang, M Kadhim, TL Ng… - Modern Pathology, 2023 - Elsevier
The diagnosis of oral epithelial dysplasia is based on the degree of architectural and
cytologic atypia in the squamous epithelium. The conventional grading system of mild …
cytologic atypia in the squamous epithelium. The conventional grading system of mild …
p53 Immunohistochemistry Patterns Are Surrogate Biomarkers for TP53 Mutations in Gastrointestinal Neuroendocrine Neoplasms
J Li, J Wang, D Su, X Nie, Y Liu, L Teng… - Gastroenterology …, 2021 - Wiley Online Library
Aims. The aim of this study was to establish p53 immunohistochemistry (IHC) patterns to
predict TP53 mutations in gastrointestinal neuroendocrine neoplasms (GI‐NENs) and to …
predict TP53 mutations in gastrointestinal neuroendocrine neoplasms (GI‐NENs) and to …
Involvement of Felis catus papillomavirus type 2 in the tumorigenesis of feline Merkel cell carcinoma
S Ito, JK Chambers, A Sumi… - Veterinary …, 2022 - journals.sagepub.com
Merkel cell carcinoma (MCC) is a cutaneous neuroendocrine tumor. We recently
demonstrated that cats with MCC often have other proliferative cutaneous lesions, such as …
demonstrated that cats with MCC often have other proliferative cutaneous lesions, such as …
Utilization of p53 and p16 Immunohistochemistry in the Classification of Human Papillomavirus–Associated, p53 Wild-Type, and p53 Abnormal Oral Epithelial …
R Novack, E Chapman, J Gao, B Horst, LN Hoang… - Modern Pathology, 2023 - Elsevier
Abstract p53 immunohistochemistry (IHC) has recently been shown to be a clinically useful
marker for predicting risk of progression to invasive squamous cell carcinoma in oral …
marker for predicting risk of progression to invasive squamous cell carcinoma in oral …