Patterns are ubiquitous in living systems and underlie the dynamic organization of cells,
tissues, and embryos. Mathematical frameworks have been devised to account for the self …

The red flour beetle Tribolium castaneum has emerged as an important insect model system
for a variety of topics. With respect to studying gene function, it is second only to the vinegar …

There is now compelling evidence that many arthropods pattern their segments using a
clock-and-wavefront mechanism, analogous to that operating during vertebrate …

The existence of discrete phenotypic traits suggests that the complex regulatory processes
which produce them are functionally modular. These processes are usually represented by …

Oscillatory and sequential processes have been implicated in the spatial patterning of many
embryonic tissues. For example, molecular clocks delimit segmental boundaries in …

Bilaterality–the possession of two orthogonal body axes–is the name-giving trait of all
bilaterian animals. These body axes are established during early embryogenesis and serve …

Sequential segmentation creates modular body plans of diverse metazoan embryos,,–.
Somitogenesis establishes the segmental pattern of the vertebrate body axis. A molecular …

Drosophila segmentation is a well-established paradigm for developmental pattern
formation. However, the later stages of segment patterning, regulated by the “pair-rule” …

In multicellular organisms, cellular behaviour is tightly regulated to allow proper embryonic
development and maintenance of adult tissue. A critical component in this control is the …

Drosophila patterning genes often contain pairs of primary and shadow enhancers that
possess overlapping activities [1–5]. It has been suggested that this regulatory" redundancy" …